Results 21 to 30 of about 116,620,127 (129)

Regulation of phoPR and cydABCD promoters of Bacillus subtilis by catabolite control protein A (CcpA).

, 2007
Regulation of phoPR and cydABCD promoters of Bacillus subtilis by catabolite control protein A (CcpA)
Ankita. Puri (8000390)
core   +6 more sources

Gene expression and metabolic activity of Streptococcus mutans during exposure to dietary carbohydrates glucose, sucrose, lactose, and xylitol

Molecular Oral Microbiology, Volume 38, Issue 5, Page 424-441, October 2023., 2023
Abstract Recent RNA sequencing studies have given us a deeper insight into the cariogenic impact of carbohydrate sources in the bacterium Streptococcus mutans, the principal microbial agent in dental caries etiopathogenesis. The process of dental caries development is facilitated by the ability of this bacterium to ferment some carbohydrates into ...
Veronika Jurakova, Veronika Farková, Jiri Kucera, Katerina Dadakova, Martina Zapletalova, Katerina Paskova, Roman Reminek, Zdenek Glatz, Lydie Izakovicova Holla, Filip Ruzicka, Jan Lochman, Petra Borilova Linhartova   +11 more
wiley   +1 more source

The fadXDEBA locus of Staphylococcus aureus is required for metabolism of exogenous palmitic acid and in vivo growth

Molecular Microbiology, Volume 120, Issue 3, Page 425-438, September 2023., 2023
Staphylococcus aureus persists on humans in lipid rich environments. Palmitic acid is abundant on skin and in plasma but is a poor substrate for S. aureus incorporation into phospholipid through the fatty acid kinase FakA pathway, which is its only known option to metabolize palmitic acid.
Robert C. Kuiack, Stephen W. Tuffs, Karine Dufresne, Robert Flick, John K. McCormick, Martin J. McGavin   +5 more
wiley   +1 more source

A model industrial workhorse: Bacillus subtilis strain 168 and its genome after a quarter of a century

Microbial Biotechnology, Volume 16, Issue 6, Page 1203-1231, June 2023., 2023
The reference genome of Bacillus subtilis was first sequenced and annotated 25 years ago. At that time, some 42% of the coding sequences could not be assigned a function. In the present annotated update, 15% of the CDS remain functionless. An important contribution of newly identitied functions has been attributed to nucleic acid modifying enzymes and ...
Erhard Bremer, Alexandra Calteau, Antoine Danchin, Colin Harwood, John D. Helmann, Claudine Médigue, Bernhard O. Palsson, Agnieszka Sekowska, David Vallenet, Abril Zuniga, Cristal Zuniga   +10 more
wiley   +1 more source

Impact of the catabolite control protein CcpA in "Staphylococcus aureus" [PDF]

, 2008
The catabolite control protein CcpA is the main regulator of carbon catabolite repression and activation in low-GC Gram-positive bacteria. In the presence of glucose, CcpA regulates gene expression by binding to so-called catabolite responsive elements ...
Seidl, K
core   +2 more sources

CcpA-Knockout Staphylococcus aureus Induces Abnormal Metabolic Phenotype via the Activation of Hepatic STAT5/PDK4 Signaling in Diabetic Mice

Pathogens, 2023
Catabolite control protein A (CcpA), an important global regulatory protein, is extensively found in S. aureus. Many studies have reported that CcpA plays a pivotal role in regulating the tricarboxylic acid cycle and pathogenicity.
Yilang Li, Jiaxuan Cai, Yinan Liu, Conglin Li, Xiaoqing Chen, Wing-Leung Wong, Wenyue Jiang, Yuan Qin, Guiping Zhang, Ning Hou, Wenchang Yuan   +10 more
doaj   +1 more source

A Flexible Binding Site Architecture Provides New Insights into CcpA Global Regulation in Gram-Positive Bacteria

mBio, 2017
Catabolite control protein A (CcpA) is the master regulator in Gram-positive bacteria that mediates carbon catabolite repression (CCR) and carbon catabolite activation (CCA), two fundamental regulatory mechanisms that enable competitive advantages in ...
Yunpeng Yang, Lu Zhang, He Huang, Chen Yang, Sheng Yang, Yang Gu, Weihong Jiang   +6 more
doaj   +1 more source

LipR functions as an intracellular pH regulator in Bacillus thuringiensis under glucose conditions

mLife, Volume 2, Issue 1, Page 58-72, March 2023., 2023
Abstract Intracellular pH critically affects various biological processes, and an appropriate cytoplasmic pH is essential for ensuring bacterial growth. Glucose is the preferred carbon source for most heterotrophs; however, excess glucose often causes the accumulation of acidic metabolites, lowering the intracellular pH and inhibiting bacterial growth.
Xia Cai, Jiaxin Qin, Xuelian Li, Taoxiong Yuan, Bing Yan, Jun Cai   +5 more
wiley   +1 more source

Role of glucose and CcpA in capsule expression and virulence of Streptococcus suis [PDF]

, 2011
Streptococcus suis is one of the most important pathogens in pigs and is also an emerging zoonotic agent. After crossing the epithelial barrier, S. suis causes bacteraemia, resulting in meningitis, endocarditis and bronchopneumonia.
Smith, H.E., Smith, H E, H. E. Smith, R. Goethe, Rohde, Manfred, Valentin-Weigand, P., M. Rohde, Goethe, R, J. Willenborg, Willenborg, J, de Greeff, A, Goethe, R., Willenborg, J., A. de Greeff, Valentin-Weigand, P, De Greeff, A., Greeff, A., De, P. Valentin-Weigand, Fulde, M., M. Fulde, Fulde, M, Rohde, M.   +21 more
core   +1 more source

Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation [PDF]

, 2022
Catabolite control protein A (CcpA) of the human pathogen Staphylococcus aureus is an essential DNA regulator for carbon catabolite repression and virulence, which facilitates bacterial survival and adaptation to a changing environment.
Liao, Xiangwen, Chen, Yushou, Xia, Wei, Guo, Yu, He, Xiaojun, Li, Hongyan, Li, Huinan, Sun, Hongzhe, Yang, Fang, Mao, Zong Wan   +9 more
core   +1 more source