Results 91 to 100 of about 3,043 (217)

Ovarian Failure-Resistant Effects of Catalpol in Aged Female Rats

open access: yesBiological and Pharmaceutical Bulletin, 2014
Catalpol, an iridoid glycoside obtained from various natural sources, has many biological functions. However, its ovarian failure-resistant effect has scarcely been studied. The present study used senile 14-month-old Sprague-Dawley female rats to examine the in vivo ovarian failure-resistant activity of catalpol. Daily oral graded doses of catalpol (1,
Min, Wei   +3 more
openaire   +3 more sources

Pramipexole protective effect on rotenone induced neurotoxicity in mice [PDF]

open access: yes, 2011
Introduction: Pramipexole is a new dopaminergic drug which has been approved for PD treatment. However, we tried to find a new capacity for this drug rather than symptomatic effect. Materials and Methods: A chronic
Abdelaziz A. Ghanem   +6 more
core   +1 more source

Protective effect of catalpol on isoproterenol-induced myocardial injury in Wistar rats [PDF]

open access: yes, 2015
The neuroprotective effects of catalpol had been well demonstrated in many studies. Nevertheless, little work was done to investigate the cardioprotective effects of catalpol.
Bi, Fang-Jie   +3 more
core   +2 more sources

Association Between Traditional Chinese Medicine Use and Sepsis Risk and Glucocorticoid Exposure in Patients With Systemic Lupus Erythematosus: A Retrospective Cohort Study

open access: yesInternational Journal of Rheumatic Diseases, Volume 28, Issue 8, August 2025.
ABSTRACT Aim Sepsis greatly increases morbidity and mortality in patients with systemic lupus erythematosus (SLE). Conventional treatments, particularly glucocorticoids (GCs), raise infection risk. This retrospective cohort study aims to investigate the association of Traditional Chinese Medicine (TCM) use with sepsis incidence, mortality, and GC ...
Chiao‐Hsuan Chu   +6 more
wiley   +1 more source

Kutkins- A Review of Chemistry and Pharmacology [PDF]

open access: yes, 2004
Kutkins are group of pharmacologically active compounds present in Picrorhiza kurroa Royle (Scrophulariaceae). Picrorhiza kurroa is traditionally known as kutki and has intense bitter taste.
Singh, Amrit Pal
core   +2 more sources

Inhibition of Taq DNA polymerase by catalpol.

open access: yesCellular and molecular biology (Noisy-le-Grand, France), 2004
Fil: Ciuffo, Gladys Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto Multidisciplinario de Investigaciones Biológicas
Pungitore, Carlos Rodolfo   +4 more
openaire   +2 more sources

Phytotherapy for Bacillus cereus: A review of the most important medicinal plants of Iran effective on B. cereus [PDF]

open access: yes, 2016
Infectious diseases are spreading day-to-day with excessive health care costs. Bacillus cereus is a known causative agent of foodborne diseases. Because of emergence of antibiotic resistance, it is necessary to develop nature- and plant-based antibiotics.
Bahmani, M.   +2 more
core  

Neuroprotection of Catalpol for Experimental Acute Focal Ischemic Stroke: Preclinical Evidence and Possible Mechanisms of Antioxidation, Anti-Inflammation, and Antiapoptosis [PDF]

open access: yes, 2017
Neuroprotection is defined as using a therapy that affects the brain tissue in the still-viable ischemic penumbra to salvage or delay the infarction. Catalpol, the main active principle of the root of Radix Rehmanniae, was reported to have pleiotropic ...
Chun-shuo Shan   +6 more
core   +2 more sources

Derivatives of grindelic acid: from a non-active natural diterpene to synthetic antitumor derivatives [PDF]

open access: yes, 2013
Using several reactions that include homologations and asymmetric epoxidations as well as Ugi and Huisgen couplings, we generated a small focused library of new derivatives from the labdane-type diterpene grindelic acid. These compounds were evaluated as
Chiaramello, Alejandra Ilda   +7 more
core   +3 more sources

Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway

open access: yesDrug Design, Development and Therapy, 2019
Hui-Feng Zhu,1,* Yali Shao,1,* Lei Qin,1,* Jing-Huan Wang,1 Shan Feng,1 Yun-Bin Jiang,1 Dong Wan2 1Department of Pharmacy, College of Pharmaceutical Sciences and Chinese Medicine, Southwest University, Chongqing 400715, People’s Republic of China ...
Zhu HF   +6 more
doaj  

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