Localization of the Catalytic Domain of Copepod Luciferases: Analysis of Truncated Mutants of the Metridia longa Luciferase [PDF]
Life, 2023 Luciferases from copepods Metridia longa and Gaussia princeps are successfully used as bioluminescent reporters for in vivo and in vitro assays. Here, we report the minimal sequence of copepod luciferases required for bioluminescence activity that was ...
Svetlana V. Markova +3 more
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The Catalytic Domain of Neuropathy Target Esterase Influences Lipid Droplet Biogenesis and Lipid Metabolism in Human Neuroblastoma Cells [PDF]
Metabolites, 2022 As an endoplasmic reticulum (ER)-anchored phospholipase, neuropathy target esterase (NTE) catalyzes the deacylation of lysophosphatidylcholine (LPC) and phosphatidylcholine (PC).
Lin He +5 more
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The Catalytic Domain Mediates Homomultimerization of MT1-MMP and the Prodomain Interferes with MT1-MMP Oligomeric Complex Assembly [PDF]
Biomolecules, 2022 Homomultimerization of MT1-MMP (membrane type 1 matrix metalloproteinase) through the hemopexin, transmembrane, and cytoplasmic domains plays a very important role in the activation of proMMP-2 and the degradation of pericellular collagen.
Marton Fogarasi, Simona Dima
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Crystal structure of the catalytic domain of human RPTPH. [PDF]
Acta Crystallogr F Struct Biol Commun, 2022 Receptor-type protein tyrosine phosphatases (RPTPs) receive extracellular stimuli and transfer them into cells. They regulate cell growth, differentiation and death via specific signals. They have also been implicated in cancer, diabetes and neurological diseases.
Kim M, Ryu SE.
europepmc +3 more sources
Phospholipid binding to the FAK catalytic domain impacts function. [PDF]
PLoS ONE, 2017 Focal adhesion kinase is an essential nonreceptor tyrosine kinase that plays an important role in development, in homeostasis and in the progression of human disease.
Jessica E Hall, Michael D Schaller
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Anti-staphylococcal activities of lysostaphin and LytM catalytic domain [PDF]
BMC Microbiology, 2012 Background Lysostaphin and the catalytic domain of LytM cleave pentaglycine crossbridges of Staphylococcus aureus peptidoglycan. The bacteriocin lysostaphin is secreted by Staphylococcus simulans biovar staphylolyticus and directed against the cell walls
Sabala Izabela +3 more
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Effects of N-Terminal Non-catalytic Domains on Enzymatic Properties of the Alginate Lyase AlgL7 from Microbulbifer sp. ALW1 [PDF]
Shipin Kexue, 2023 In order to clarify the effect of the non-catalytic carbohydrate-binding module (CBM) and F5/8 type C domains on the enzymatic properties of AlgL7, an alginate lyase from Microbulbifer sp. ALW1, the full-length enzyme AlgL7 and two truncated enzymes: CD1
HUANG Xiaoyi, LI Hebin, CHEN Yanhong, JIANG Zedong, NI Hui, LI Qingbiao, ZHU Yanbing,
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Marine Drugs, 2022 Alginate is abundant in the cell walls of brown algae. Alginate lyases can degrade alginate, and thus play an important role in the marine carbon cycle and industrial production.
Xiao-Meng Sun +7 more
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Minimal catalytic domain of N-acetylglucosaminyltransferase V [PDF]
Glycobiology, 2000 UDP-GlcNAc: Manalpha1-6Manbeta-R beta1-6 N-acetylglucosaminyltransferase V (EC 2.4.1.155, GlcNAc-TV) is a Golgi enzyme that substitutes the trimannosyl core in the biosynthetic pathway for complex-type N-linked glycans. GlcNAc-TV activity is regulated by oncogenes frequently activated in cancer cells ( ras, src, and her2/neu ) and by activators of T ...
Korczak B. +4 more
openaire +3 more sources
Journal of Integrative Agriculture, 2020 FgGCN5, a GCN5 homolog in Fusarium graminearum, plays a critical role in hyphal vegetative growth, asexual and sexual reproduction, deoxynivalenol (DON) biosynthesis and plant infection.
Qian-nan WANG +2 more
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