Results 141 to 150 of about 26,847 (292)
Beyond monofunctionality: structural perspectives on phenol oxidase side activity in a catalase
Acta Crystallographica Section D, EarlyView.Structural and biochemical characterization of the extracellular fungal catalase ClCPO uncovers an unexpected phenol oxidase promiscuity. Crystal structures, substrate docking and electron‐transfer pathway analysis identify ligand‐binding regions and support a working mechanistic model for catalase‐associated phenol oxidase activity.Catalases are ...
Christina Ferousi +5 more
wiley +1 more source
The FEBS Journal, EarlyView.In Colletotrichum acutatum species complex, conserved ring‐cleavage dioxygenases located adjacent to AA5_2 enzymes were investigated as potential redox partners. Biochemical analyses identified the dioxygenases as intradiol‐cleaving enzymes preferentially oxidizing methyl‐substituted catechols, while AA5_2 enzymes displayed weak alcohol oxidase ...
Radka Končitíková +7 more
wiley +1 more source
International Journal of Cosmetic Science, EarlyView.This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques +6 more
wiley +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger +5 more
wiley +1 more source
Catechins in stroke: multi-target mechanisms, preclinical evidence, and translational challenges. [PDF]
Front PharmacolZhang Y, Wang S, Yuan Q.
europepmc +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
A study on the differences in recovery effects of different types of nutritional supplements on competitive performance of esports athletes under mental fatigue. [PDF]
J Int Soc Sports NutrChong Y +5 more
europepmc +1 more source
Investigating Overweight and Obesity Risk in Shift Workers Using Omics Technologies
Obesity Reviews, EarlyView.ABSTRACT Night shift workers are at higher risk of developing overweight and obesity. The disruption of the physiological circadian rhythm leads to metabolic alterations, such as decreased insulin sensitivity, increased adipogenesis, and inflammation, with effects on their health and leading, among other diseases, to obesity.
Katrin Scionti +3 more
wiley +1 more source
Anticancer potential of <i>Reynoutria japonica</i> Houtt. <i>in vitro</i> root extract on lymphoma cell lines. [PDF]
Front PharmacolSroka J +7 more
europepmc +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao +7 more
wiley +1 more source