Results 91 to 100 of about 2,348,941 (273)

Mackey functors on compact closed categories

, 2007
We develop and extend the theory of Mackey functors as an application of enriched category theory. We define Mackey functors on a lextensive category $\E$ and investigate the properties of the category of Mackey functors on $\E$.
Panchadcharam, Elango, Street, Ross
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Infinitesimal Structure of Singularities

Universe, 2017
Some important problems of general relativity, such as the quantisation of gravity or classical singularity problems, crucially depend on geometry on very small scales.
Michael Heller, Jerzy Król
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Semi-Substructural Logics à la Lambek with Symmetry

Bulletin of the Section of Logic
This work studies the proof theory and ternary relational semantics of left (right) skew monoidal closed categories and skew monoidal bi-closed categories, both symmetric and non-symmetric, from the perspective of non-associative Lambek calculus ...
Cheng-Syuan Wan
doaj   +1 more source

Category Theory-Based Mobile User Interface Pattern Recommendation Method

IEEE Access, 2019
Although using the mobile user interface pattern (MUIP) can increase the efficiency and quality of mobile interface development, the existing pattern search methods have some limitations to provide appropriate patterns for solving a given design problem.
Wei Jia, Qingyi Hua, Minjun Zhang, Bo Wang, Rui Chen, Xiang Ji   +5 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Physical computing: a category theoretic perspective on physical computation and system compositionality

Journal of Physics: Complexity
This paper introduces a category theory-based framework to redefine physical computing in light of advancements in quantum computing and non-standard computing systems.
Nima Dehghani, Gianluca Caterina
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Coinductive Streams in Monoidal Categories [PDF]

Logical Methods in Computer Science
We introduce monoidal streams. Monoidal streams are a generalization of causal stream functions, which can be defined in cartesian monoidal categories, to arbitrary symmetric monoidal categories. In the same way that streams provide semantics to dataflow
Elena Di Lavore, Giovanni de Felice, Mario Román   +2 more
doaj   +1 more source