Results 101 to 110 of about 8,086,442 (367)

Robert Rosen’s Relational Biology Theory and His Emphasis on Non-Algorithmic Approaches to Living Systems

open access: yesMathematics
This paper examines the use of algorithms and non-algorithmic models in mathematics and science, especially in biology, during the past century by summarizing the gradual development of a conceptual rationale for non-algorithmic models in biology. First,
Patricia A. Lane
doaj   +1 more source

ANALYSIS OF POSSIBILITIES TO PRESENT FORMALLY THE ELEMENTS OF VIRTUAL EDUCATIONAL SPACE [PDF]

open access: yesAvtomobilʹnyj Transport (Harʹkov), 2017
For formal representation of virtual educational space elements, the paper considers the topology methods, in particularly the methods for categories and functors theory, allowing for solving semistructured and indeterminate problems and reflecting their
О. Morozova
doaj  

A triangulated category without models [PDF]

open access: yesarXiv, 2007
We exhibit a triangulated category which is neither the stable category of a Frobenius category nor a full triangulated subcategory of the homotopy category of a stable model category.
arxiv  

Category Spanning, Evaluation, and Performance: Revised Theory and Test on the Corporate Law Market

open access: yes, 2016
Studies suggest that category-spanning organizations receive lower evaluation and perform worse than organizations focused on a single category. We propose that (a) these effects are contingent on clients’ theory of value, and that, as clients expect ...
Lionel Paolella, Rodolphe Durand
semanticscholar   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Architecture, Analysis, and Design of Systems Using Extensions of Category Theory

open access: yesIEEE Open Journal of Systems Engineering
The engineering of systems has lacked the scientific and mathematical underpinnings enjoyed by traditional engineering disciplines. Earlier work of the authors formulated advanced mathematical methods for architecture definition and the use of model ...
Charles E. Dickerson   +1 more
doaj   +1 more source

The zeta function of a finite category [PDF]

open access: yesarXiv, 2012
We define the zeta function of a finite category. And we propose a conjecture which states the relationship between the Euler characteristic of finite categories and the zeta function of finite categories. This conjecture is verified when categories are finite groupoids, finite acyclic categories, categories with 2-objects and finite categories ...
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

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