Results 71 to 80 of about 205,037 (299)
Advanced Functional Materials, EarlyView.Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan +4 more
wiley +1 more source
World Journal of Surgical Oncology, 2007 Background β-catenin is a multifunctional protein involved in two apparently independent processes: cell-cell adhesion and signal transduction. β-catenin is involved in Wnt signaling pathway that regulates cellular differentiation and proliferation.
Shinoda Noriyuki +10 more
doaj +1 more source
δ-Catenin activates Rho GTPase, promotes lymphangiogenesis and growth of tumor metastases. [PDF]
PLoS ONE, 2015 δ-Catenin, an adherens junctions protein, is not only involved in early development, cell-cell adhesion and cell motility in neuronal cells, but it also plays an important role in vascular endothelial cell motility and pathological angiogenesis.
Sampa Ghose, Yongfen Min, P Charles Lin
doaj +1 more source
β‐Catenin in the Melanocyte Lineage
Pigment Cell Research, 2003 β‐Catenin is a multifunctional protein involved in cell–cell adhesion, intracellular signalling and gene transcription. It has been implicated in the development of various lineages, including neural crest derivatives. Melanocytes are derived from neural crest cells and β‐catenin is expressed throughout the development of this cell lineage.
Larue, L, Kumasaka, M, Goding, C
openaire +2 more sources
The many faces and functions of β-catenin [PDF]
The EMBO Journal, 2012 β-Catenin (Armadillo in Drosophila) is a multitasking and evolutionary conserved molecule that in metazoans exerts a crucial role in a multitude of developmental and homeostatic processes. More specifically, β-catenin is an integral structural component of cadherin-based adherens junctions, and the key nuclear effector of canonical Wnt signalling in ...
Valenta, Tomas +2 more
openaire +4 more sources
Advanced Functional Materials, EarlyView.The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai +9 more
wiley +1 more source
Journal of Oral and Maxillofacial Pathology, 2015 β catenin belongs to the armadillo family of proteins. It plays a crucial role in developmental and homeostatic processes. Wnts are a family of 19 secreted glycoproteins that transduce multiple signaling cascades, including the canonical Wnt/β catenin pathway, Wnt/Ca(2+) pathway and the Wnt/polarity pathway.
Sharada Prakash, Uma Swaminathan
openaire +3 more sources
Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration
Advanced Functional Materials, EarlyView.A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo +10 more
wiley +1 more source
Genome Biology, 2019 Background Circular RNAs are a class of regulatory RNA transcripts, which are ubiquitously expressed in eukaryotes. In the current study, we evaluate the function of a novel circRNA derived from the β-catenin gene locus, circβ-catenin.
Wei-Cheng Liang +10 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu +7 more
wiley +1 more source