Results 81 to 90 of about 205,037 (299)
Advanced Healthcare Materials, EarlyView.This study introduces a controllable degradation system for Mg‐based biomaterials using sputtering technology, marking a significant advancement in nerve regeneration research. The Mg‐sputtered nerve conduits demonstrate enhanced biocompatibility, biofunctionality, mechanical compatibility, and precise magnesium release, resulting in improved axonal ...
Hyewon Kim +12 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang +11 more
wiley +1 more source
P53 and Beta-Catenin Activity during Estrogen treatment of Osteoblasts
Cancer Cell International, 2005 Background This study was undertaken to examine the relationship between the tumor suppressor gene p53 and the nuclear signaling protein beta-catenin during bone differentiation.
Kolman Kevin +4 more
doaj +1 more source
p120-catenin: Past and present
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2007 p120-catenin was first described in 1989 as a Src substrate whose phosphorylation correlated with transformation. It was identified by cDNA cloning in 1992, and shown to interact with cadherins in 1994. Though enigmatic for some time, p120 has emerged as a master regulator of cadherin stability, and an important modulator of RhoGTPase activities.
openaire +3 more sources
Advanced Materials, EarlyView.This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang +3 more
wiley +1 more source
Biochemistry and Biophysics Reports, 2018 Transcription factor lymphoid-enhancer–binding factor 1 (LEF-1) is a key molecule in the Wnt/β-catenin signaling pathway. Slug is one of the Wnt/β-catenin target genes and can induce epithelial–mesenchymal transition (EMT). Previously, we have shown that
Wakako Kobayashi, Masayuki Ozawa
doaj
Heterogeneous beta-catenin activation is sufficient to cause hepatocellular carcinoma in zebrafish
Biology Open, 2019 Up to 41% of hepatocellular carcinomas (HCCs) result from activating mutations in the CTNNB1 gene encoding β-catenin. HCC-associated CTNNB1 mutations stabilize the β-catenin protein, leading to nuclear and/or cytoplasmic localization of β-catenin and ...
Sharanya M. Kalasekar +5 more
doaj +1 more source
Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases
Advanced Materials, EarlyView.This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu +16 more
wiley +1 more source
Advanced Materials, EarlyView.Surprisingly, a cell can bind to itself to make a self‐adhesion, which engineered here to improve how cells attach to biomaterials. Nanoprinting are used to make 3D structures smaller than cells–called Self‐Adhesion‐Tunnels (SATs)–around which cells can wrap and bind to themselves.
Anamika Singh +4 more
wiley +1 more source
A transphyletic study of metazoan β-catenin protein complexes
Zoological LettersBeta-catenin is essential for diverse biological processes, such as body axis determination and cell differentiation, during metazoan embryonic development.
Ivan Mbogo +9 more
doaj +1 more source