Results 41 to 50 of about 10,852 (292)
World Journal of Surgical Oncology, 2008 Background The E-cadherin catenin system acts as an invasion suppressor of epithelial malignancies. However, it is debatable whether expression of E-cadherin or catenins is a useful prognostic marker in invasive breast cancer.
Mansel Robert E +3 more
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Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesis. [PDF]
PLoS ONE, 2012 Alpha (α)-E-catenin is a component of the cadherin complex, and has long been thought to provide a link between cell surface cadherins and the actin skeleton.
Sumeda Nandadasa +4 more
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Tyrosine phosphatase activity is restricted by basic charge substituting mutation of substrates
Scientific Reports, 2022 Phosphorylation controls important cellular signals and its dysregulation leads to disease. While most phospho-regulation studies are focused on kinases, phosphatases are comparatively overlooked. Combining peptide arrays with SAMDI mass spectrometry, we
Che-Fan Huang +2 more
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Acta Cirúrgica Brasileira, 2021 Purpose: To evaluate the effects of sucralfate enemas in tissue contents of E-cadherin and ?-catenin in an experimental diversion colitis. Methods: Thirty-six male Wistar rats were submitted to a proximal colostomy and a distal mucous fistula. They were
Daniela Tiemi Sato +6 more
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Journal of the American Society of Nephrology, 2012 Wnt/ β -catenin signaling plays a significant role during kidney development and maturation.[1][1][][2]–[3][3] β -Catenin, the canonical Wnt signal transducer, is involved in nephron induction[4][4],[5][5] and branching morphogenesis.[1][1],[6][6] Importantly, β -catenin modulation is ...
openaire +2 more sources
γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin [PDF]
, 2012 Canonical Wnt signaling regulates the transcription of T-cell factor (TCF)-responsive genes through the stabilization and nuclear translocation of the transcriptional co-activator, β-catenin.
A Gandillet +51 more
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Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]
, 2002 Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core +2 more sources
Adherens junctions remain dynamic
BMC Biology, 2010 One of the four principal categories of cell-cell junctions that hold together and shape distinct tissues and organs in vertebrates, adherens junctions (AJs) form cell-cell contacts that connect transmembrane proteins with cytoskeletal actin filaments to
Falk Matthias M
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Loss of ctnnd2b affects neuronal differentiation and behavior in zebrafish
Frontiers in Neuroscience, 2023 Delta-catenin (CTNND2) is an adhesive junction associated protein belonging to the family of p120 catenins. The human gene is located on the short arm of chromosome 5, the region deleted in Cri-du-chat syndrome (OMIM #123450). Heterozygous loss of CTNND2
Raquel Vaz +5 more
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S-Nitrosation of β-Catenin and p120 Catenin [PDF]
Circulation Research, 2012 Rationale: Endothelial adherens junction proteins constitute an important element in the control of microvascular permeability. Platelet-activating factor (PAF) increases permeability to macromolecules via translocation of endothelial nitric oxide synthase (eNOS) to cytosol and stimulation of eNOS ...
Marin, Natalie +9 more
openaire +3 more sources