Results 31 to 40 of about 83,980 (287)
p120 Catenin-Associated Fer and Fyn Tyrosine Kinases Regulate β-Catenin Tyr-142 Phosphorylation and β-Catenin-α-Catenin Interaction [PDF]
Molecular and Cellular Biology, 2003 beta-Catenin has a key role in the formation of adherens junction through its interactions with E-cadherin and alpha-catenin. We show here that interaction of beta-catenin with alpha-catenin is regulated by the phosphorylation of beta-catenin Tyr-142. This residue can be phosphorylated in vitro by Fer or Fyn tyrosine kinases.
Jose, Piedra +6 more
openaire +2 more sources
Development, 2016 Cadherins are crucial for the radial migration of excitatory projection neurons into the developing neocortical wall. However, the specific cadherins and the signaling pathways that regulate radial migration are not well understood.
I. Martinez-Garay +5 more
semanticscholar +1 more source
S-Nitrosation of β-Catenin and p120 Catenin [PDF]
Circulation Research, 2012 Rationale: Endothelial adherens junction proteins constitute an important element in the control of microvascular permeability. Platelet-activating factor (PAF) increases permeability to macromolecules via translocation of endothelial nitric oxide synthase (eNOS) to cytosol and stimulation of eNOS ...
Marin, Natalie +9 more
openaire +3 more sources
Cadherins and catenins in dendrite and synapse morphogenesis
Cell Adhesion & Migration, 2015 Neurons are highly polarized specialized cells. Neuronal integrity and functional roles are critically dependent on dendritic architecture and synaptic structure, function and plasticity.
E. Seong, L. Yuan, J. Arikkath
semanticscholar +1 more source
Folia Histochemica et Cytobiologica, 2010 The E-cadherin-catenin complex plays an important role in the process of cell adhesion. Its dysfunction is associated with a decrease in cell differentiation and with increased invasiveness and metastasis.
Marek Ustymowicz +4 more
doaj +1 more source
World Journal of Surgical Oncology, 2008 Background The E-cadherin catenin system acts as an invasion suppressor of epithelial malignancies. However, it is debatable whether expression of E-cadherin or catenins is a useful prognostic marker in invasive breast cancer.
Mansel Robert E +3 more
doaj +1 more source
New Functions for Alpha-Catenins in Health and Disease: From Cancer to Heart Regeneration
Cell and Tissue Research, 2015 Strong cell–cell adhesion mediated by adherens junctions is dependent on anchoring the transmembrane cadherin molecule to the underlying actin cytoskeleton.
A. Vite, Jifen Li, G. Radice
semanticscholar +1 more source
Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesis. [PDF]
PLoS ONE, 2012 Alpha (α)-E-catenin is a component of the cadherin complex, and has long been thought to provide a link between cell surface cadherins and the actin skeleton.
Sumeda Nandadasa +4 more
doaj +1 more source
Alpha-Catenins Control Cardiomyocyte Proliferation by Regulating Yap Activity
Circulation Research, 2014 Rationale: Shortly after birth, muscle cells of the mammalian heart lose their ability to divide. Thus, they are unable to effectively replace dying cells in the injured heart.
Jifen Li +7 more
semanticscholar +1 more source
Journal of the American Society of Nephrology, 2011 Congenital anomalies of the kidney and urinary tract are the single most common cause of renal failure in childhood. Advances in the care of children with renal failure has primarily focused on optimizing the supportive, although nonspecific, treatment of chronic kidney disease and in addressing ...
Jacqueline Ho, Carlton M. Bates
openaire +1 more source