Results 21 to 30 of about 10,852 (292)

Exchange of catenins in cadherin–catenin complex [PDF]

Oncogene, 2003
beta-Catenin is an intracellular multifunctional protein. In complex with the transmembrane adhesive receptor E-cadherin, it becomes plasma membrane-associated and mediates intercellular adhesion. A cytosolic pool of beta-catenin interacts with DNA-binding proteins and participates in signal transduction. To reveal the possible cross-talk between these
Klingelhöfer, Jörg, Troyanovsky, Regina B, Laur, Oscar Y, Troyanovsky, Sergey   +3 more
openaire   +3 more sources

Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases

Frontiers in Cell and Developmental Biology, 2022
The function and structure of the mammalian epithelial cell layer is maintained by distinct intercellular adhesion complexes including adherens junctions (AJs), tight junctions, and desmosomes.
Lindyann R. Lessey, Shaiya C. Robinson, Roopali Chaudhary, Juliet M. Daniel   +3 more
doaj   +1 more source

Adhesion molecules in Wilms tumor (part I) [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2003
Adhesion molekues are glicoprotees which have extracellular, transmembranous and intracytoplasmatic part. They show their basic role is in cell interaction in the tissue on one side and between cells and matrix on the other side.
Basta-Jovanović Gordana M., Radojević Sanja M., Đuričić Slaviša M.   +2 more
doaj   +1 more source

Antagonism between wild-type and mutant β-catenin controls hepatoblastoma differentiation via fascin-1

JHEP Reports, 2023
Background & Aims: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours.
Caroline Gest, Sandra Sena, Lydia Dif, Véronique Neaud, Robin Loesch, Nathalie Dugot-Senant, Lisa Paysan, Léo Piquet, Terezinha Robbe, Nathalie Allain, Doulaye Dembele, Catherine Guettier, Paulette Bioulac-Sage, Anne Rullier, Brigitte Le Bail, Christophe F. Grosset, Frédéric Saltel, Valérie Lagrée, Sabine Colnot, Violaine Moreau   +19 more
doaj   +1 more source

Expression of β-Catenin and γ-Catenin in Maxillary Bone Regeneration [PDF]

International Journal of Immunopathology and Pharmacology, 2011
β- and γ-catenin are components of catenin family involved in cadherin adhesion function. Recently it has been shown that this family is involved in other functions such as signaling and activation of transcription factors. The final goal of this study was to evaluate the role of β- and γ-catenin in bone cell physiology and bone regeneration. Formalin-
A. SANTARELLI, G. COLELLA, F. CARINCI, G. PANNONE, R. RUBINI, L. LO RUSSO, POLIMENI, Antonella, N. SGARAMELLA, ANNIBALI, Susanna, G. SPINELLI, L. LO MUZIO   +10 more
openaire   +4 more sources

Differential Regulation of Growth-Promoting Signalling Pathways by E-Cadherin [PDF]

, 2010
Background: Despite the well-documented association between loss of E-cadherin and carcinogenesis, as well as the link between restoration of its expression and suppression of proliferation in carcinoma cells, the ability of E-cadherin to modulate growth-
Dawn C. Walker, Jennifer Southgate, Kurt Anderson, Lisa A. Kirkwood, Nikolaos T. Georgopoulos   +4 more
core   +8 more sources

Identification of the Domain of α-Catenin Involved in Its Association with β-Catenin and Plakoglobin (γ-Catenin) [PDF]

Journal of Biological Chemistry, 1997
alpha-Catenin is a 102-kDa protein exhibiting homology to vincuin, and it forms complexes with cadherins or the tumor-suppressor gene product adenomatous polyposis coli through binding to beta-catenin or plakoglobin (gamma-catenin). The incorporation of alpha-catenin into the cadherin-catenin complexes is a prerequisite for expression of the cell ...
H, Obama, M, Ozawa
openaire   +2 more sources

The catenin family at a glance [PDF]

Journal of Cell Science, 2010
Members of the catenin family were first isolated complexed with the cytoplasmic domains of cadherins at cell-cell junctions, and this relationship is considered one of the defining aspects of catenins. Their functions at such contacts are multifaceted and remain under active study and discussion.
Pierre D, McCrea, Dongmin, Gu
openaire   +2 more sources

The potential involvement of E-cadherin and beta-catenins in meningioma. [PDF]

PLoS ONE, 2010
OBJECTIVE: To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS: Immunohistochemistry staining was performed on samples from patients with meningioma.
Keiyu Zhou, Guangtao Wang, Yirong Wang, Hanghuang Jin, Shuxu Yang, Chibo Liu   +5 more
doaj   +1 more source

Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling [PDF]

, 2012
The functions of many organs depend on the generation of an epithelium. The transition from a set of loosely connected nonpolarized cells to organized sheets of closely associated polarized epithelial cells requires the assembly of specialized cell ...
Pieters, Tim, van Hengel, Jolanda, Van Roy, Frans   +2 more
core   +2 more sources