Results 21 to 30 of about 5,972 (292)
Scribble, Lgl1, and myosin IIA interact with α-/β-catenin to maintain epithelial junction integrity
Cell Adhesion & Migration, 2023 E-cadherin-catenin complex together with the cytoskeleton, builds the core of Adherens junctions (AJs). It has been reported that Scribble stabilizes the coupling of E-cadherin with catenins promoting epithelial cell adhesion, but the mechanism remains ...
Maha Abedrabbo +4 more
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p120 Catenin-Associated Fer and Fyn Tyrosine Kinases Regulate β-Catenin Tyr-142 Phosphorylation and β-Catenin-α-Catenin Interaction [PDF]
Molecular and Cellular Biology, 2003 beta-Catenin has a key role in the formation of adherens junction through its interactions with E-cadherin and alpha-catenin. We show here that interaction of beta-catenin with alpha-catenin is regulated by the phosphorylation of beta-catenin Tyr-142. This residue can be phosphorylated in vitro by Fer or Fyn tyrosine kinases.
Jose, Piedra +6 more
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S-Nitrosation of β-Catenin and p120 Catenin [PDF]
Circulation Research, 2012 Rationale: Endothelial adherens junction proteins constitute an important element in the control of microvascular permeability. Platelet-activating factor (PAF) increases permeability to macromolecules via translocation of endothelial nitric oxide synthase (eNOS) to cytosol and stimulation of eNOS ...
Marin, Natalie +9 more
openaire +3 more sources
Folia Histochemica et Cytobiologica, 2010 The E-cadherin-catenin complex plays an important role in the process of cell adhesion. Its dysfunction is associated with a decrease in cell differentiation and with increased invasiveness and metastasis.
Marek Ustymowicz +4 more
doaj +1 more source
New insights into the evolution of metazoan cadherins and catenins
, 2013 E-Cadherin and b-catenin are the best studied representatives of the superfamilies of transmembrane cadherins and intracellular armadillo catenins, respectively.
Gül, Ismail SahinUGent00007100197680200106693597975271727416E6D8D0-F0EE-11E1-A9DE-61C894A0A6B4 +3 more
core +2 more sources
World Journal of Surgical Oncology, 2008 Background The E-cadherin catenin system acts as an invasion suppressor of epithelial malignancies. However, it is debatable whether expression of E-cadherin or catenins is a useful prognostic marker in invasive breast cancer.
Mansel Robert E +3 more
doaj +1 more source
Journal of the American Society of Nephrology, 2011 Congenital anomalies of the kidney and urinary tract are the single most common cause of renal failure in childhood. Advances in the care of children with renal failure has primarily focused on optimizing the supportive, although nonspecific, treatment of chronic kidney disease and in addressing ...
Jacqueline Ho, Carlton M. Bates
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Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesis. [PDF]
PLoS ONE, 2012 Alpha (α)-E-catenin is a component of the cadherin complex, and has long been thought to provide a link between cell surface cadherins and the actin skeleton.
Sumeda Nandadasa +4 more
doaj +1 more source
Tyrosine phosphatase activity is restricted by basic charge substituting mutation of substrates
Scientific Reports, 2022 Phosphorylation controls important cellular signals and its dysregulation leads to disease. While most phospho-regulation studies are focused on kinases, phosphatases are comparatively overlooked. Combining peptide arrays with SAMDI mass spectrometry, we
Che-Fan Huang +2 more
doaj +1 more source
Acta Cirúrgica Brasileira, 2021 Purpose: To evaluate the effects of sucralfate enemas in tissue contents of E-cadherin and ?-catenin in an experimental diversion colitis. Methods: Thirty-six male Wistar rats were submitted to a proximal colostomy and a distal mucous fistula. They were
Daniela Tiemi Sato +6 more
doaj +1 more source