Results 21 to 30 of about 6,280 (288)
Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases
Frontiers in Cell and Developmental Biology, 2022 The function and structure of the mammalian epithelial cell layer is maintained by distinct intercellular adhesion complexes including adherens junctions (AJs), tight junctions, and desmosomes.
Lindyann R. Lessey +3 more
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Adhesion molecules in Wilms tumor (part I) [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2003 Adhesion molekues are glicoprotees which have extracellular, transmembranous and intracytoplasmatic part. They show their basic role is in cell interaction in the tissue on one side and between cells and matrix on the other side.
Basta-Jovanović Gordana M. +2 more
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JHEP Reports, 2023 Background & Aims: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours.
Caroline Gest +19 more
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Expression of β-Catenin and γ-Catenin in Maxillary Bone Regeneration [PDF]
International Journal of Immunopathology and Pharmacology, 2011 β- and γ-catenin are components of catenin family involved in cadherin adhesion function. Recently it has been shown that this family is involved in other functions such as signaling and activation of transcription factors. The final goal of this study was to evaluate the role of β- and γ-catenin in bone cell physiology and bone regeneration.
A. SANTARELLI +10 more
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Identification of the Domain of α-Catenin Involved in Its Association with β-Catenin and Plakoglobin (γ-Catenin) [PDF]
Journal of Biological Chemistry, 1997 alpha-Catenin is a 102-kDa protein exhibiting homology to vincuin, and it forms complexes with cadherins or the tumor-suppressor gene product adenomatous polyposis coli through binding to beta-catenin or plakoglobin (gamma-catenin). The incorporation of alpha-catenin into the cadherin-catenin complexes is a prerequisite for expression of the cell ...
H, Obama, M, Ozawa
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The catenin family at a glance [PDF]
Journal of Cell Science, 2010 Members of the catenin family were first isolated complexed with the cytoplasmic domains of cadherins at cell-cell junctions, and this relationship is considered one of the defining aspects of catenins. Their functions at such contacts are multifaceted and remain under active study and discussion.
Pierre D, McCrea, Dongmin, Gu
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The potential involvement of E-cadherin and beta-catenins in meningioma. [PDF]
PLoS ONE, 2010 OBJECTIVE: To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS: Immunohistochemistry staining was performed on samples from patients with meningioma.
Keiyu Zhou +5 more
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Beyond β-catenin: prospects for a larger catenin network in the nucleus [PDF]
Nature Reviews Molecular Cell Biology, 2015 β-catenin is widely regarded as the primary transducer of canonical WNT signals to the nucleus. In most vertebrates, there are eight additional catenins that are structurally related to β-catenin, and three α-catenin genes encoding actin-binding proteins that are structurally related to vinculin.
Pierre D, McCrea, Cara J, Gottardi
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Structure of the Dimerization and β-Catenin- Binding Region of α-Catenin [PDF]
Molecular Cell, 2000 In adherens junctions, alpha-catenin links the cadherin-beta-catenin complex to the actin-based cytoskeleton. alpha-catenin is a homodimer in solution, but forms a 1:1 heterodimer with beta-catenin. The crystal structure of the alpha-catenin dimerization domain, residues 82-279, shows that alpha-catenin dimerizes through formation of a four-helix ...
Pokutta, Sabine, Weis, William I.
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Expression of the E-cadherin-catenin complex in patients with pancreatic ductal adenocarcinoma.
Folia Histochemica et Cytobiologica, 2010 Cadherins and catenins, mediators of intercellular interactions, play a major role in adhesion. Changes in their expression and functioning reflect invasive and metastatic properties of cancer cells.
Katarzyna Guzińska-Ustymowicz +3 more
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