Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity
Synapse formation involves reciprocal interactions between cells resulting in formation of a structure optimized for efficient information transfer. Recent work has implicated constituents of the cadherin–catenin cell-adhesion complex in both synapse ...
Louis Reichardt, Jyothi Arikkath
exaly +2 more sources
Adhesive But Not Lateral E-cadherin Complexes Require Calcium and Catenins for Their Formation
We examined intercadherin interactions in epithelial A-431 cells producing endogenous E-cadherin and recombinant forms of E-cadherin tagged either by myc or by flag epitopes. Three distinct E-cadherin complexes were found.
Sergey Troyanovsky
exaly +2 more sources
Expression of catenins and E-cadherin during epithelial restitution in inflammatory bowel disease
Catenins are cytoplasmic proteins associated with E‐cadherin, the prime mediator of cell–cell adhesion. Perturbation in any of these molecules results in altered intercellular adhesion, cell differentiation, and increased migration.
Massimo Pignatelli +2 more
exaly +2 more sources
Intact Mass Profiling Reveals Phospho‐Proteoforms of the Catenins (85–110 kDa) Regulated by Actomyosin Contractility [PDF]
Che-Fan Huang +2 more
exaly +2 more sources
Catenins: Keeping Cells from Getting Their Signals Crossed
Mirna Pérez-Moreno, Elaine Fuchs
exaly +2 more sources
Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex
Pascale Cossart +2 more
exaly +2 more sources
Computational modeling of the interplay between cadherin-mediated cell adhesion and Wnt signaling pathway. [PDF]
Wnt signaling and cadherin-mediated adhesion have been implicated in both processes of embryonic development and the progression of carcinomas. Recent experimental studies revealed that Wnt signaling and cadherin-mediated cell adhesion have close ...
Jiawen Chen, Zhong-Ru Xie, Yinghao Wu
doaj +1 more source
Exchange of catenins in cadherin–catenin complex [PDF]
beta-Catenin is an intracellular multifunctional protein. In complex with the transmembrane adhesive receptor E-cadherin, it becomes plasma membrane-associated and mediates intercellular adhesion. A cytosolic pool of beta-catenin interacts with DNA-binding proteins and participates in signal transduction. To reveal the possible cross-talk between these
Klingelhöfer, Jörg +3 more
openaire +3 more sources
Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases
The function and structure of the mammalian epithelial cell layer is maintained by distinct intercellular adhesion complexes including adherens junctions (AJs), tight junctions, and desmosomes.
Lindyann R. Lessey +3 more
doaj +1 more source

