Results 161 to 170 of about 191,378 (381)

Immunostained cathepsins B and L correlate with depth of invasion and different metastatic pathways in early stage gastric carcinoma [PDF]

, 2000
Akiharu Dohchin, Junichi Suzuki, Hideyuki Seki, Manabu Masutani, Hiroshi Shiroto, Yoshikazu Kawakami   +5 more
openalex   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study

Frontiers in Immunology
BackgroundDiabetic retinopathy (DR) is a major microvascular complication of diabetes and a leading cause of blindness worldwide. The pathogenesis of DR involves complex interactions between metabolic disturbances, immune cells, and proteolytic enzymes ...
Huijun Zhou, Jingzhi Wang, Xuehao Cui, Xuehao Cui   +3 more
doaj   +1 more source

Proteinases [PDF]

, 1993
Fritz, Hans, Jochum, Marianne, Machleidt, W., Neuhof, H., Redl, H., Schlag, Günther   +5 more
core   +1 more source

Inhibition of cathepsin L ameliorates inflammation through the A20/NF-κB pathway in endotoxin-induced acute lung injury [PDF]

Shiyi Yang, Kaijun Chen, Jinkang Yu, Zhangchu Jin, Min Zhang, Zhouyang Li, Yang Yu, Nanxia Xuan, Baoping Tian, Na Li, Zhengtong Mao, Wenbing Wang, Tianpeng Chen, Yinfang Wu, Yun Zhao, Min Zhang, Fei Xia, Songmin Ying, Wen Li, Fugui Yan, Xingxian Zhang, Gensheng Zhang, Huahao Shen, Zhihua Chen   +23 more
openalex   +1 more source

A two‐sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy

Epilepsia Open, EarlyView.
Abstract Objective This study aims to investigate the causal relationship between cathepsins and epilepsy, using Mendelian randomization (MR) and mediation analysis. Methods Publicly accessible summary statistics on epilepsy were obtained from FinnGen and the International League Against Epilepsy Consortium.
Huaiyu Sun, Di Ma, Wuqiong Zhang, Shuai Hou, Zhiqing Chen, Xuewei Li, Hongmei Meng, Daguang Zhang   +7 more
wiley   +1 more source

Homology of amino acid sequences of rat liver cathepsins B and H with that of papain.

, 1983
Koji Takio, Takae Towatari, Nobuhiko Katunuma, D.C. Teller, Koiti Titani   +4 more
openalex   +2 more sources

The α1/2 helical backbone of the prodomains defines the intrinsic inhibitory specificity in the cathepsin L‐like cysteine protease subfamily [PDF]

, 2000
Ying Guo, Ursula Kurz, Joachim E. Schultz, Chin Chia Lim, Bernd Wiederanders, Klaus Schilling   +5 more
openalex   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Cathepsin S, a new serum biomarker of sarcoidosis discovered by transcriptome analysis of alveolar macrophages.

, 2019
Hiroyuki Tanaka, Etsuro Yamaguchi, Nobuhiro Asai, Toyoharu Yokoi, Masaki Nishimura, Haruhisa Nakao, Masashi Yoneda, Yoshinori Ohtsuka, Satoshi Konno, Noritaka Yamada   +9 more
openalex   +2 more sources