Results 181 to 190 of about 102,381 (252)

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Targeted lysosomal activation in bladder epithelium enhances clearance of intracellular uropathogenic Escherichia coli. [PDF]

PLoS Pathog
Tomasek K, Skurvydaite K, Paduthol G, Burns AM, Schlunke L, Borgeat V, Pasquali C, Romani M, McKinney JD.   +8 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

SARS-CoV-2 enhances lysosomal exocytosis and deacidifies lysosomes to facilitate viral release. [PDF]

mLife
Qin F, Yan C, Liu Z, Wang D, Zhong H, Ding Q, Chen M, Zhang XE.   +7 more
europepmc   +1 more source

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

Journal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu, Yuan Chen, Mario Romandini, Håvard Jostein Haugen, Sašo Ivanovski   +4 more
wiley   +1 more source

ADORA2A activation restores lysosomal function and photoreceptor outer segment degradation in stressed retinal pigment epithelium. [PDF]

Front Physiol
Tao D, Zhou D, Wu M, Xie P, Zhang Y, Bao J.   +5 more
europepmc   +1 more source

Diagnostic Biomarkers of Periodontitis and Peri‐Implantitis: The Past, the Present, the Future

Journal of Periodontal Research, EarlyView.
Diagnostic biomarkers of periodontitis and peri‐implantititis from the past, through the present, and into the future. ABSTRACT In this narrative review we present our perspective on the past, present and future of periodontal and peri‐implantitis diagnostic biomarkers.
Denis F. Kinane, Başak Bıyıkoğlu
wiley   +1 more source

Assessment of the Binding Affinity of Covalent Inhibitors of Cruzain and Cathepsin L Using Relative Binding Free Energy. [PDF]

ChemMedChem
Magno YC, Barbosa LF, Oliveira MVD, Lameira J, Montanari CA.   +4 more
europepmc   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

Aggressive Periodontitis and Palmoplantar Keratoderma: Papillon-Lefèvre Syndrome in an 11-Year-Old Nepalese Girl. [PDF]

Clin Case Rep
Bhattarai J, Pokhrel S, Poudel Y, Rimal U.   +3 more
europepmc   +1 more source