Results 231 to 240 of about 12,525,351 (366)

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Muscle Cathepsin B Treatment Improves Behavioral and Neurogenic Deficits in a Mouse Model of Alzheimer's Disease. [PDF]

Aging Cell
Pinto A, Haytural H, Loss CM, Alvarez C, Ertas A, Curtis O, Williams AR, Murphy G, Salleng KJ, Gografe S, Visavadiya NP, Khamoui AV, Altıntaş A, Kafri T, Barres R, Deshmukh AS, van Praag H.   +16 more
europepmc   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Cathepsin B hyperactivation facilitates exosome release of CVB3 particles and exacerbation of acute pancreatitis by impairing lysosomal integrity and acidification. [PDF]

mBio
Liang T, Zhang Z, Xu L, Sun Z, Xu W.
europepmc   +1 more source

Cathepsin B Improves ß-Amyloidosis and Learning and Memory in Models of Alzheimer’s Disease

, 2016
Christine M. Embury, Bhagyalaxmi Dyavarshetty, Yaman Lu, Jayme Wiederin, Paweł Ciborowski, Howard E. Gendelman, Tomomi Kiyota   +6 more
openalex   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Targeting the miR-96-5p/Cathepsin B Pathway to Alleviate Neuron-Derived Neuroinflammation in Alzheimer's Disease. [PDF]

MedComm (2020)
Zheng K, Huang HZ, Liu D, Brazhe N, Chen J, Zhu LQ.   +5 more
europepmc   +1 more source

Enteropathogenic E. coli effector Map interacts with Rab13 and regulates the depletion of the tight junction proteins occludin and claudins via cathepsin B-mediated mechanisms [PDF]

Anupam Mandal, Pangertoshi Walling, Shamim Akhtar Qureshi, Kritika Kansal, Saima Aijaz   +4 more
openalex   +1 more source

Salivary Proteomic Signatures in Pregnant Women With Excessive Gingival Bleeding

Oral Diseases, EarlyView.
ABSTRACT Objective This observational, cross‐sectional, and analytical study aimed to explore the pathophysiological mechanisms of gingivitis in pregnancy by analyzing the salivary proteomic profile according to gingival bleeding status. Materials and Methods Pregnant women at the 27th week of gestation or beyond were categorized into two groups: those
Gerson Aparecido Foratori‐Junior, Clovis Bergamin Griso, Amanda Borges Pirondi, Laura Teodoro de Marchi, Talita Mendes Oliveira Ventura, Larissa Tercilia Grizzo, Roosevelt da Silva Bastos, Alejandra Chaparro, Nagihan Bostanci, Marília Afonso Rabelo Buzalaf   +9 more
wiley   +1 more source

Computational studies of copper and palladium II complex with potential anticancer activity involving topoisomerase II alpha and cathepsins B and L

, 2023
Hilário Moniz Buanar
openalex   +1 more source