Results 41 to 50 of about 12,525,351 (366)
The Role of Cathepsin B in Peritoneal Fibrosis due to Peritoneal Dialysis
International Journal of Nephrology, 2019 Glucose-containing peritoneal dialysis (PD) solution causes peritoneal fibrosis (PF) characterized by accumulation of extracellular matrix (ECM) in the submesothelial layer.
Su Ah Sung +4 more
doaj +1 more source
Biomedicines, 2023 Cathpesin B is a multi-functional protease that plays numerous roles in physiology and pathophysiology. We hypothesized that actin cytoskeleton proteins that are substrates of cathepsin B, various lipids, and kinases that are regulated by lipids would be
Tamim Kawakibi +5 more
doaj +1 more source
The Role of Cathepsin D in the Pathophysiology of Heart Failure and its Potentially Beneficial Properties:a translational approach [PDF]
, 2019 Aims: Cathepsin D is a ubiquitous lysosomal protease that is primarily secreted due to oxidative stress. The role of circulating cathepsin D in heart failure (HF) is unknown.
Adriaan A. Voors +16 more
core +3 more sources
Immune Mechanisms Involved in Schistosoma mansoni-Cathepsin B Vaccine Induced Protection in Mice
Frontiers in Immunology, 2018 A vaccine against schistosomiasis would contribute to a long-lasting decrease in disease spectrum and transmission. Our previous protection studies in mice using Schistosoma mansoni Cathepsin B (Sm-Cathepsin B) resulted in 59 and 60% worm burden ...
Alessandra Ricciardi +7 more
doaj +1 more source
Cathepsin B cleavage of the trypsinogen activation peptide
BMC Gastroenterology, 2002 Background Cathepsin B is thought to play a central role in intrapancreatic trypsinogen activation and the onset of pancreatitis. A recent investigation of the cathepsin B mediated activability of wildtype trypsinogen and their mutations N29I, N29T and ...
Keim Volker, Bödeker Hans, Teich Niels
doaj +1 more source
Cathepsin B-deficient mice as source of monoclonal anti-cathepsin B antibodies [PDF]
Biological Chemistry, 2014 Abstract Cathepsin B has been demonstrated to be involved in several proteolytic processes that support tumor progression and metastasis and neurodegeneration. To further clarify its role, defined monoclonal antibodies are needed.
Weber, Ekkehard +7 more
openaire +3 more sources
Peptide synthesis by recombinant Fasciola hepatica cathepsin L1 [PDF]
, 2006 Synthesis of the tripeptide Z-Phe-Arg-SerNH2 has been accomplished by a recombinant cysteine protease, cathepsin L1 from liver fluke (Fasciola hepatica), using Z-Phe-Arg-OMe as acyl acceptor and SerNH2 as nucleophile in 0.1 M ammonium acetate pH 9.0–12.5%
Ciarán Ó'Fágáin +16 more
core +1 more source
Cloning and analysis of cathepsin B gene of Radopholus similis
浙江大学学报. 农业与生命科学版, 2013 The banana burrowing nematode, Radopholus similis, is a migratory endoparasite plant nematode and severely harms many tropical and subtropical crops. It is the most important invasive species to banana worldwide, and is listed as a quarantine pest in ...
LI Danlei +4 more
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Molecules, 2023 TMAO is a new risk biomarker for cardiovascular disease. With trimethylammonium as its main chemical skeleton, TMAO is structurally similar to many endogenous metabolites, such as acetylcholine, carnitine, phosphorylcholine, etc. The mechanism of TMAO on
Dongyu Lei +6 more
doaj +1 more source
Frontiers in Microbiology, 2023 Tomato disease is an important disease affecting agricultural production, and the combined infection of tomato chlorosis virus (ToCV) and tomato yellow leaf curl virus (TYLCV) has gradually expanded in recent years, but no effective control method has ...
Ding-Yi-Hui Lu +17 more
doaj +1 more source