Results 161 to 170 of about 113,729 (277)

Expression and prognostic significance of cathepsin D in acute myeloid leukemia. [PDF]

Medicine (Baltimore)
Han H, Huang Y, Xie J, Liu J, Wang W.
europepmc   +1 more source

Hypoxia Exacerbates Periapical Periodontitis‐Associated Pathological Bone Loss via the Hypoxia‐Inducible Factor‐2α‐Calmodulin‐Dependent Protein Kinase IV Axis

Cell Proliferation, EarlyView.
Hypoxia exposure activates HIF‐2α, which binds to the Camk4 promoter to enhance RANKL‐mediated osteoclast differentiation, leading to aggravated alveolar bone resorption in periapical periodontitis. ABSTRACT Periapical periodontitis is one of the most common inflammatory bone destructive diseases. Epidemiological evidence suggests that hypoxia exposure,
Kang Gao, Yifan Xu, Haoran Du, Zixiao Li, Xiaochen Fang, Minghui Wang, Jia Liu, Xu Zha, Xianglong Han, Weihua Guo, Xicheng Liu, Jian Zhou   +11 more
wiley   +1 more source

Circulating Cathepsin D Exacerbates Injury-Induced Brain Damage by Promoting Neutrophil Infiltration Into the Brain. [PDF]

J Am Heart Assoc
Liang Y, Zhao D, Wu PF, Liang YQ, Zhang XW, Xing J, Sun X, An MX, Shi JX, Gao QH, Tian L, Sun HZ, Xue B, Jiang LB, Chen YH, Zhao WD.   +15 more
europepmc   +1 more source

Physicochemical characterization of etch‐and‐rinse adhesive system doped with catechin‐loaded polymeric microparticles

European Journal of Oral Sciences, EarlyView.
Abstract This study evaluated the incorporation of epigallocatechin‐3‐gallate (EGCG)‐loaded poly(lactide‐co‐glycolide) (PLGA) microparticles into a two‐step etch‐and‐rinse adhesive and their effects on physicochemical properties and EGCG release. EGCG was added to Single Bond 2 either directly (0.01% and 0.1% w/w) or encapsulated in PLGA 50:50 or 75:25
Jiovanne Rabelo Neri, Nadine Luisa Guimarães Albuquerque, Marcelo Victor Sidou Lemos, Monica Yamauti, Francisco Fábio Oliveira de Sousa, Vanara Florêncio Passos, Sérgio Lima Santiago   +6 more
wiley   +1 more source

Design and Preclinical Evaluation of First ⁶⁸Ga-Labeled Cathepsin D-Targeted Radiotracers. [PDF]

J Med Chem
Xi Y, Wang X, Ji M, Zhang J, Xu X, He S, Song S.   +6 more
europepmc   +1 more source

Enhanced Osteocyte Differentiation: Cathepsin D and L Secretion by Human Adipose-Derived Mesenchymal Stem Cells. [PDF]

Cells, 2023
Choi JW, Lim S, Jung SE, Jeong S, Moon H, Song BW, Kim IK, Lee S, Hwang KC, Kim SW.   +9 more
europepmc   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer. [PDF]

Cell Rep Med
Zhan W, Fu Y, Liu Y, Cai R, Bai F, Guo C, Cheng Y, Wu Z, Qin G, Xie Y, Zhang J, Deng Y.   +11 more
europepmc   +1 more source

Cathepsin D Inhibits Angiogenesis in Pituitary Neuroendocrine Tumors. [PDF]

Acta Histochem Cytochem, 2022
Fujiwara R, Ten H, Chen H, Jiang CL, Oyama KI, Onoda K, Matsuno A.   +6 more
europepmc   +1 more source

Phagocyte proteinases in multiple trauma and sepsis [PDF]

, 1993
Fritz, Hans, Holaday, J. W., Jochum, Marianne, Machleidt, W., Neugebauer, E.   +4 more
core   +1 more source