Results 161 to 170 of about 66,677 (282)

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Unraveling the mystery of peripartum cardiomyopathy; Cathepsin D. [PDF]

Am Heart J Plus
Hendricks ED, Parker AM.
europepmc   +1 more source

Cathepsin D protects renal tubular cells from damage induced by high glucose independent of its enzymatic activity.

, 2017
Feng Du, Tian Wang, Si Li, Xin Meng, Haiyan Zhang, Detian Li, Zhen‐Xian Du, Hua‐Qin Wang   +7 more
openalex   +1 more source

A replacement of the active-site aspartic acid residue 293 in mouse cathepsin D affects its intracellular stability, processing and transport in HEK-293 cells [PDF]

, 2002
Sanna Partanen, Stephan Storch, Hans‐Gerhard Löffler, Andrej Hasilík, Jaana Tyynelä, Thomas Braulke   +5 more
openalex   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

The FEBS Journal, EarlyView.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte, Mariana N. R. Trujilho, Karolaine S. S. M. Valdivia, Aline F. Araujo, Laura M. C. de Lorena, Vinicius H. de Oliveira, Beatriz V. Pereira, Emilly R. Leme, Wagner A. S. Júdice, Maurício F. M. Machado   +9 more
wiley   +1 more source

Structural Congeners of Izenamides Responsible for Cathepsin D Inhibition: Insights from Synthesis-Derived Elucidation. [PDF]

Mar Drugs, 2023
Kim HS, Kong H, Kim T, Lim C, Lee S, Kim SH, Suh YG.   +6 more
europepmc   +1 more source

Processing of human cathepsin D in lysosomes in vitro.

, 1985
Volkmar Gieselmann, Andrej Hasilík, Kurt Von Figura   +2 more
openalex   +1 more source

Regulation of Cathepsin D Metabolism in Rabbit Heart [PDF]

, 1982
Allen M. Samarel, E. A. OGUNRO, Alan Ferguson, Patricia A. Allenby, Michael Lesch   +4 more
openalex   +1 more source

Diagnosing oncocytic renal tumours on renal mass biopsy; pathological concordance and the impact of evolving classification

Histopathology, EarlyView.
Overall, there was good concordance between renal mass biopsy and subsequent diagnosis at nephrectomy or repeat biopsy in oncocytic renal neoplasms. Some discordant cases were reclassified as emerging tumour entities (LOT, EVT), indicating that greater recognition of these entities may help reduce diagnostic uncertainty and improve biopsy ...
Shifaa' Al Qa'qa', Carol C Cheung, Satheesh Krishna, Antonio Finelli, Susan Prendeville   +4 more
wiley   +1 more source

Localization of Alkaline Phosphatase and Cathepsin D during Cell Restoration after Colchicine Treatment in Primary Cultures of Fetal Rat Hepatocytes

, 2011
Kohsuke Chida, Meiko Taguchi
openalex   +2 more sources