Results 171 to 180 of about 66,677 (282)

Influence of cathepsin D expression on prognosis in non-small cell lung cancer [PDF]

, 2000
Hyung Roul Youm, Jae Il Myeong, Jong Chul Lim, Han Kyun Kim, Nam Hun Lee, Dae Ho Lee, Hyang Mee Ko, Jong Yeoung Moon, Heon Seok Kang, Heong Seon Rheu, Wan Kim, Chang Soo Park, Kyung Ok Park   +12 more
openalex   +1 more source

Effects of Kudoa thyrsites on Proximate Composition and Texture of Merluccius capensis and Zues capensis

Journal of Fish Diseases, EarlyView.
ABSTRACT Kudoa thyrsites is a myxosporean endoparasite that infects fish, frequently resulting in myoliquefaction, impacting the texture and eating quality of fish muscle. The aim of this study was to investigate the effects of K. thyrsites infection on the proximate composition and texture parameters of raw fillets from two South African economically ...
Sune St Clair Henning, Thanduxolo Phakathi   +1 more
wiley   +1 more source

Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals. [PDF]

Proc Natl Acad Sci U S A, 2022
Pedram K, Laqtom NN, Shon DJ, Di Spiezio A, Riley NM, Saftig P, Abu-Remaileh M, Bertozzi CR.   +7 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

A Dual-Function "TRE-Lox" System for Genetic Deletion or Reversible, Titratable, and Near-Complete Downregulation of Cathepsin D. [PDF]

Int J Mol Sci, 2023
Terron HM, Maranan DS, Burgard LA, LaFerla FM, Lane S, Leissring MA.   +5 more
europepmc   +1 more source

Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.

, 1993
Eric T. Baldwin, Talapady N. Bhat, Sergei Gulnik, M.V. Hosur, Raymond C. Sowder, Raúl E. Cachau, Jack Collins, A M Silva, John W. Erickson   +8 more
openalex   +2 more sources

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Cathepsin D inhibits AGEs-induced phenotypic transformation in vascular smooth muscle cells. [PDF]

Sci Rep
He X, Tian S, Bu L, Zhao X, Zheng L, Zhang P, Guo R, Ma M.   +7 more
europepmc   +1 more source

New multienzymatic complex formed between human cathepsin D and snake venom phospholipase A₂. [PDF]

J Venom Anim Toxins Incl Trop Dis, 2022
Moraes JDN, Francisco AF, Dill LM, Diniz RS, de Oliveira CS, da Silva TMR, Caldeira CADS, Corrêa EA, Coutinho-Neto A, Zanchi FB, Fontes MRM, Soares AM, Calderon LA.   +12 more
europepmc   +1 more source