Results 191 to 200 of about 66,677 (282)

Grassystatin G, a new cathepsin D inhibitor from marine cyanobacteria: discovery, synthesis, and biological characterization. [PDF]

RSC Med Chem
Elsadek LA, Seabra G, Paul VJ, Luesch H.
europepmc   +1 more source

Inhibition of cathepsin D by substrate analogs containing statine and by analogs of pepstatin

, 1986
Nirankar S. Agarwal, Daniel H. Rich
openalex   +1 more source

Transcriptional activation of cathepsin D gene expression by growth factors [PDF]

, 2000
F Wang, Renqin Duan, John M. Chirgwin, SH Safe   +3 more
openalex   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Targeted demethylation of cathepsin D via epigenome editing rescues pathology in Alzheimer's disease mouse model. [PDF]

Theranostics
Park M, Ryu H, Heo S, Kim B, Park J, Lim KH, Han SB, Park H.   +7 more
europepmc   +1 more source

Cathepsin D precursors in clathrin-coated organelles from human fibroblasts. [PDF]

, 1985
Eckhard Schulze-Lohoff, Andrej Hasilík, Kurt Von Figura   +2 more
openalex   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Inhibition of intracellular versus extracellular cathepsin D differentially alters the liver lipidome of mice with metabolic dysfunction-associated steatohepatitis. [PDF]

FEBS J
Vermeulen I, Li M, van Mourik H, Yadati T, Eijkel G, Balluff B, Godschalk R, Temmerman L, Biessen EAL, Kulkarni A, Theys J, Houben T, Cillero-Pastor B, Shiri-Sverdlov R.   +13 more
europepmc   +1 more source

Molecular cloning of mouse cathepsin D

Nucleic Acids Research, 1990
M J, Grusby, S C, Mitchell, L H, Glimcher   +2 more
openaire   +3 more sources

Thyroglobulin processing by thyroidal proteases. Major sites of cleavage by cathepsins B, D, and L.

, 1991
A D Dunn, HELEN E. CRUTCHFIELD, John T. Dunn   +2 more
openalex   +1 more source