Results 211 to 220 of about 16,299,323 (310)

Structural elucidation and antiviral activity of cathepsin L inhibitors with carbonyl and epoxide warheads

, 2023
Falke S, Lieske J, Herrmann A, Loboda J, Günther S, Reinke PY, Ewert W, Karničar K, Usenik A, Lindič N, Sekirnik A, Tsuge H, Turk V, Chapman HN, Hinrichs W, Ebert G, Turk D, Meents A.   +17 more
europepmc   +1 more source

Long‐term stability of sinus complication management

Periodontology 2000, EarlyView.
Abstract Maxillary sinus augmentation shows a low incidence of complications and high clinical success due to favorable biological conditions and typically transient issues. Most complications are intraoperative, such as Schneiderian membrane perforation or hemorrhage, and are often resolved immediately.
Pablo Galindo‐Moreno, Tiziano Testori, Miguel Padial‐Molina, Allinson Olaechea, Francisco O'Valle, Pablo Galindo‐Fernandez   +5 more
wiley   +1 more source

Dual Inhibitors of SARS-CoV-2 3CL Protease and Human Cathepsin L Containing Glutamine Isosteres Are Anti-CoV-2 Agents. [PDF]

J Am Chem Soc
Kumar V, Zhu J, Chenna BC, Hoffpauir ZA, Rademacher A, Rogers AM, Tseng CT, Drelich A, Farzandh S, Lamb AL, Meek TD.   +10 more
europepmc   +1 more source

Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo

Nature Communications, 2014
Martina Tholen, L. E. Hillebrand, S. Tholen, Oliver Sedelmeier, S. Arnold, T. Reinheckel   +5 more
semanticscholar   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Discovering novel Cathepsin L inhibitors from natural products using artificial intelligence. [PDF]

Comput Struct Biotechnol J
Li Q, Zhou SR, Kim H, Wang H, Zhu JJ, Yang JK.   +5 more
europepmc   +1 more source

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon, Marion Mosca, Nadège Milhau, Mélanie Legain, Adrien Idée, Didier Pin   +5 more
wiley   +1 more source

Evaluation of Reproductive Histology Response of Adult Fasciola hepatica in Goats Vaccinated with Cathepsin L Phage-Exposed Mimotopes. [PDF]

Int J Mol Sci
Villa-Mancera A, Maldonado-Hidalgo J, Robles-Robles M, Olivares-Pérez J, Olmedo-Juárez A, Rodríguez-Castillo J, Pérez-Mendoza N, Utrera-Quintana F, Pérez J, Ortega-Vargas S.   +9 more
europepmc   +1 more source

Macrobrachium rosenbergii cathepsin L: molecular characterization and gene expression in response to viral and bacterial infections.

Microbiology Research, 2013
J. Arockiaraj, Annie J. Gnanam, Dhanaraj Muthukrishnan, M. Thirumalai, Mukesh Pasupuleti, James Milton, Marimuthu Kasi   +6 more
semanticscholar   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source