Results 211 to 220 of about 108,576 (328)

Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis [PDF]

, 2018
Bukowska-Straková, Karolina, Dulak, Józef, Florczyk-Soluch, Urszula, Józefczuk, Ewelina, Józkowicz, Alicja, Mendel, Mateusz, Nowak, Witold, Stępniewski, Jacek, Viscardi, Monika   +8 more
core   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

UNC0638 inhibits SARS-CoV-2 entry by blocking cathepsin L maturation. [PDF]

J Virol
Chen Y, Shi Y, Zuo X, Dong X, Xiao X, Chen L, Xiang Z, Ren L, Zhou Z, Wei W, Lei X, Wang J.   +11 more
europepmc   +1 more source

Fighting Celiac Disease: Improvement of pH Stability of Cathepsin L In Vitro by Computational Design. [PDF]

Int J Mol Sci, 2023
Chugunov AO, Dvoryakova EA, Dyuzheva MA, Simonyan TR, Tereshchenkova VF, Filippova IY, Efremov RG, Elpidina EN.   +7 more
europepmc   +1 more source

Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain

, 2019
Paul D. Boudreau, Bailey W. Miller, Laura‐Isobel McCall, Jehad Almaliti, Raphael Reher, Ken Hirata, Thu Bao Le, Jair L. Siqueira-Neto, Vivian Hook, William H. Gerwick   +9 more
openalex   +2 more sources

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Cathepsin L and transmembrane serine protease 11E mediate trypsin-independent entry of porcine deltacoronavirus into Huh7 cells. [PDF]

J Virol
Xiao W, Xiong Y, Wang Y, Li T, Chen C, Shi Y, Su G, Zhou Y, Xiao S, Fang L.   +9 more
europepmc   +1 more source

Trichinella spiralis cathepsin L damages the tight junctions of intestinal epithelial cells and mediates larval invasion. [PDF]

PLoS Negl Trop Dis, 2023
Liu RD, Meng XY, Li CL, Lin XZ, Xu QY, Xu H, Long SR, Cui J, Wang ZQ.   +8 more
europepmc   +1 more source

Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model [PDF]

, 2016
Dhivya R. Sudhan, Christine Pampo, Lori Rice, Dietmar W. Siemann   +3 more
openalex   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source