Results 161 to 170 of about 1,249 (192)
Determination of cathinone, cathine and norephedrine in hair of Yemenite khat chewers
Forensic Science International, 2003 A sensitive and reproducible method for the quantitative determination of cathinone (CTN), norpseudoephedrine (NPE, cathine) and norephedrine (NE) from hair was developed. The compounds were extracted for 4 hours with phosphate buffer pH 2.0, followed by a standard solid phase extraction procedure on a mixed phase column, derivatization with ...
Frank, Sporkert +4 more
openaire +3 more sources
Neuropharmacology, 1981 Abstract Since it has been demonstrated that cathinone (α-aminopropiophenone) and not cathine (nor-pseudo-ephedrine), as previously accepted, is the main constituent of the young leaves and tops of khat ( Catha edulis Forsk), it has become of particular interest to elucidate the pharmacological activity of the new constituent.
E A Carlini
exaly +5 more sources
Current Alzheimer ResearchIntroduction: Khat (Catha edulis Forssk.), a stimulant plant native to Africa and Asia, contains psychoactive compounds such as cathinone and cathine that affect the central nervous system. This study aims to investigate the potential neurotoxicological risks associated with these compounds, particularly ...
Mohammed S. Alkaf +3 more
openaire +3 more sources
Phytochemical Analysis, 2017 AbstractIntroductionCatha edulis (qat, khat, mirra) is a woody plant species that is grown and consumed in East Africa and Yemen for its stimulant alkaloids cathinone, cathine and norephedrine. Two Celastraceae species, in addition to qat, have been noted for their stimulant properties in ethnobotanical literature.
Luke R. Tembrock +5 more
openaire +3 more sources
Rats become acutely tolerant to cathine after amphetamine or cathinone administration
Psychopharmacology, 1990 The drug discrimination paradigm was used to evaluate in rats the ability of the discriminate response to either 0.8 mg/kg d-amphetamine or 0.8 mg/kg l-cathinone to generalize to 2.4-6.0 mg/kg of the active cathinone metabolite d-norpseudoephedrine, also known as cathine.
Martin D. Schechter
exaly +4 more sources
Journal of Chromatography A, 2016 A literature criticism is given on methods using currently gas chromatography mass spectrometry (GC/MS) to determine cathine (CAT), cathinone (CTN) and norephedrine (NE), jointly khatamines. In this study, khatamines' oximation, trimethylsilylation and mass fragmentation properties-applying N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA), its ...
Imre Boldizsár
exaly +4 more sources
Journal of Cardiovascular PharmacologyAbstract: Amphetamine derivatives are used worldwide legally or illegally and intoxications may be accompanied by cardiac arrhythmias. Here, we tested contractile effects of cumulative applied (±)-amphetamine, pseudoephedrine, nor-pseudoephedrine (cathine), and cathinone in electrically stimulated (1 Hz) human right atrial preparations (HAP ...
Joachim, Neumann +3 more
openaire +3 more sources
, 2011 The main effect of khat assumption is a psychoactive stimulation similar to that produced by amphetamines. The substances responsible for the central nervous system stimulatory effect are alkaloids with an amphetamine-like structure: cathinone, cathine and phenylpropanolamine (PPA) [1,2].
S. Arnoldi +6 more
openaire +2 more sources