Results 81 to 90 of about 5,160 (224)
Metabolism of cathinone to (−)-norephedrine and (−)-norpseudoephedrine
Journal of Pharmacy and Pharmacology, 1986 Abstract S-(−)-Cathinone (S-(−)-α-aminopropiophenone) is the major active principle of khat leaves (Catha edulis), which are widely used in East Africa and the Arab peninsula as an amphetamine-like stimulant. After oral administration of synthesized cathinone (isomers, racemate), 22–52% was recovered in 24 h urine samples mainly as ...
R, Brenneisen +2 more
openaire +2 more sources
Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones [PDF]
, 2017 Synthetic cathinones are a new class of psychostimulant substances. Rarely, they can cause liver injury but associated mechanisms are not completely elucidated.
Krähenbühl, Stephan +2 more
core +1 more source
Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature
Ecology and Evolution, Volume 16, Issue 4, April 2026.This study explores the evolutionary role of psilocybin, the psychedelic compound found in Psilocybe mushrooms. We provide the first experimental tests of defence and community‐level evidence for invertebrate responses to psilocybin‐producing fungi, revealing significant negative effects on invertebrate locomotion, development, and survival.
K. J. Matthews Nicholass +16 more
wiley +1 more source
Monitoring new psychoactive substances use through wastewater analysis: current situation, challenges and limitations [PDF]
, 2019 New psychoactive substances (NPSs) are compounds that produce similar effects to those induced by illicit drugs (IDs), such as cocaine, cannabis, and amphetamines, but are not strictly regulated by international conventions.
Bijlsma, Lubertus +3 more
core +2 more sources
Addiction, Volume 121, Issue 4, Page 870-882, April 2026.Abstract Background and aims While the health hazards of synthetic cannabinoid receptor agonists (SCRAs) are often approximated using in vitro pharmacological parameters as surrogate, this approach fails to consider pharmacokinetic and pharmacodynamic complexity.
Michaela J. Sommer +3 more
wiley +1 more source
Electroanalysis, Volume 38, Issue 3, March 2026.Voltammetric methods on screen‐printed carbon electrodes were employed for the rapid detection of the synthetic cathinone β‐keto‐ethylbenzodioxolylbutanamine (βk‐EBDB) in supporting electrolyte and human biological fluids. The electroanalytical method is promising as a portable drug testing device for on‐site applications—providing a repeatable linear ...
Harry Van Dorssen +2 more
wiley +1 more source
Applied SciencesCathinone and its synthetic derivatives are among the most popular classes of narcotics worldwide. Experimental studies have demonstrated variable cytotoxic activity among these substances.
Natalina Makieieva, Teobald Kupka
doaj +1 more source
Psychopharmacological aspects of catha edulis (khat) and consequences of long term use: a review
Psychiatry and Behavioral Sciences, 2011 Catha edulis (khat) is a plant grown commonly in the horn of Africa. Its leaves are chewed by the local people for their stimulant action. The purpose of this review was to summarize the psychopharmacologic aspects of Catha edulis (khat) and consequences
Nasir Tajure Wabel
doaj +1 more source
Drug and Alcohol Review, Volume 45, Issue 3, March 2026.ABSTRACT Introduction Drug alerts are sometimes issued when samples are found to exceed a pre‐determined dose threshold. In Australia, it is common for alerts to be issued when MDMA pills contain ≥ 150 mg of MDMA free‐base or 179 mg hydrochloride. Nineteen such alerts were issued in Australia in 2024, raising concerns that repeat alerts may lose impact
Jack Freestone +5 more
wiley +1 more source