Results 21 to 30 of about 99,803 (245)

An extracellular cation coordination site influences ion conduction of OsHKT2;2

open access: yesBMC Plant Biology, 2019
Background HKT channels mediate sodium uniport or sodium and potassium symport in plants. Monocotyledons express a higher number of HKT proteins than dicotyledons, and it is only within this clade of HKT channels that cation symport mechanisms are found.
Janin Riedelsberger   +4 more
doaj   +1 more source

Zinc/iron-regulated transporter-like protein gene family in Theobroma cacao L: Characteristics, evolution, function and 3D structure analysis

open access: yesFrontiers in Plant Science, 2023
The zinc/iron-regulated transporter-like protein (ZIP) gene family first identified in plants is highly distributed in the plant kingdom. This family has previously been reported to transport several essential and non-essential cationic elements ...
Daniel Dastan Rezabala Pacheco   +3 more
doaj   +1 more source

Similarities and contrasts in the structure and function of the calcium transporter ATP2A1 and the copper transporter ATP7B

open access: yesSubstantia, 2018
Ca2+ and Cu2+ ATPases are enzyme proteins that utilize ATP for active transport of Ca2+ or Cu2+ across intracellular or cellular membranes.1-4 These enzymes are referred to as P-type ATPases since they utilize ATP through formation of a phosphorylated ...
Giuseppe Inesi
doaj   +1 more source

Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children [PDF]

open access: yesDrug Metabolism and Disposition, 2017
Organic cation transporter 1 (OCT1) plays an important role in the disposition of clinically important drugs, and the capacity of OCT1 activity is presumed to be proportional to the protein expression level in organ tissues. Knowledge of OCT1 protein expression in children, especially neonates and small infants, is currently very limited.
David, Hahn   +3 more
openaire   +2 more sources

An efficient strategy for small-scale screening and production of archaeal membrane transport proteins in Escherichia coli.

open access: yesPLoS ONE, 2013
BackgroundMembrane proteins play a key role in many fundamental cellular processes such as transport of nutrients, sensing of environmental signals and energy transduction, and account for over 50% of all known drug targets.
Pikyee Ma   +12 more
doaj   +1 more source

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes

open access: yesCell Reports, 2017
Proper intracellular cholesterol trafficking is critical for cellular function. Two lysosome-resident proteins, NPC1 and NPC2, mediate the egress of low-density lipoprotein-derived cholesterol from lysosomes.
Jian Wei   +10 more
doaj   +1 more source

Cation-Dependent Binding of Substrate to the Folate Transport Protein of Lactobacillus casei [PDF]

open access: yesJournal of Bacteriology, 1982
Lactobacillus casei cells grown in the presence of limiting folate contained large amounts of a membrane-associated binding protein which mediates folate transport. Binding to this protein at 4°C was time and concentration dependent and at low levels (1 to 10 nM) of folate required 60 min to reach a steady state.
G B, Henderson, S, Potuznik
openaire   +2 more sources

Protein‐Protein Interactions Between Organic Anion Transporting Polypeptide 1B3 (OATP1B3) and Organic Cation Transporter 1 (OCT1)

open access: yesThe FASEB Journal, 2015
The two drug transporters OATP1B3 and OCT1 are expressed at the basolateral membrane of human hepatocytes. In a search for potential interacting proteins a modified yeast‐two‐hybrid screen (DUALmembrane screen) identified OCT1 as an interaction partner for OATP1B3.
Jessica Shoop   +3 more
openaire   +1 more source

Urinary Excretion of Tetrodotoxin Modeled in a Porcine Renal Proximal Tubule Epithelial Cell Line, LLC-PK1

open access: yesMarine Drugs, 2017
This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal tubule epithelial cell line, LLC-PK1. Time course profiles of TTX excretion and reabsorption across the cell monolayers at 37 °C showed that the amount of
Takuya Matsumoto   +6 more
doaj   +1 more source

Salinity tolerance in plants. Quantitative approach to ion transport starting from halophytes and stepping to genetic and protein engineering for manipulating ion fluxes

open access: yesFrontiers in Plant Science, 2015
Ion transport is the fundamental factor determining salinity tolerance in plants. The Review starts from differences in ion transport between salt tolerant halophytes and salt-sensitive plants with an emphasis on transport of potassium and sodium via ...
Vadim eVolkov
doaj   +1 more source

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