Results 171 to 180 of about 1,728 (186)

Insights into sperm cell motility signaling through sNHE and the CatSpers

Molecular and Cellular Endocrinology, 2006
Successful natural reproduction normally requires vigorously motile spermatozoa. Using a signal peptide trapping strategy, we identified two new genes, a putative sperm Na+/H+ exchanger (sNHE) and the putative cation channel CatSper2, with unique and essential roles in sperm motility.
Timothy A, Quill, Dan, Wang, David L, Garbers   +2 more
openaire   +2 more sources

N-acetylcysteine Improved Expression of FSHR, LHCGR, Catsper-1, Catsper-2, and SF-1 Genes in Testis of Rats with Varicocele

Reproductive Sciences
Varicocele, a condition of insufficient oxygen supply to testicular tissue leading to hypoxia, is a major factor contributing to male infertility. This study investigated the potential protective effects of N-acetylcysteine (NAC), a potent antioxidant, on sperm characteristics and hormonal receptor expression in a rat model of varicocele-induced ...
Majid Shokoohi, Mohammad Hossein Nasr Esfahani, Amir Afshin Khaki, Gilda Ghazi Soltani, Alireza Alihemmati, Linda Mohammadzadeh Boukani   +5 more
openaire   +2 more sources

Progesterone and CatSper dependency

International Journal of Andrology, 2012
Martin, Blomberg Jensen, Stephen J, Publicover   +1 more
openaire   +2 more sources

Catspermasome: The matrimony of CatSper and SLCO6C1

Biophysical Journal, 2023
openaire   +1 more source

C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane

Cell Reports, 2022
Jae Yeon Hwang, Huafeng Wang, Yonggang Lu   +2 more
exaly  

The role of Hv1 and CatSper channels in sperm activation.

The Journal of physiology, 2011
Elevations of sperm intracellular pH and Ca(2+) regulate sperm motility, chemotaxis, capacitation and the acrosome reaction, and play a vital role in the ability of the sperm cell to reach and fertilise the egg. In human spermatozoa, the flagellar voltage-gated proton channel Hv1 is the main H(+) extrusion pathway that controls sperm intracellular pH ...
Polina V, Lishko, Yuriy, Kirichok
openaire   +1 more source

CatSper genes and their role in male infertility: A review

SKUAST Journal of Research, 2022
Syed Shanaz, Ambreen Hamadani, Sheikh Firdous, Ruksana Shah, Mubashir Ali Rather, Nusrat Nabi Khan, Nazir A. Ganai   +6 more
openaire   +1 more source

Revisiting the action of steroids and triterpenoids on the human sperm Ca2+ channel CatSper

Molecular Human Reproduction, 2020
Anders Rehfeld
exaly  

Evolutionary Genomics Reveals Lineage-Specific Gene Loss and Rapid Evolution of a Sperm-Specific Ion Channel Complex: CatSpers and CatSperβ

PLoS ONE, 2008
Xinjiang Cai, David E Clapham
exaly  

Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa

Human Reproduction, 2015
Wardah Alasmari, Sean G Brown, Stuart M Wilson   +2 more
exaly