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Is Male Infertility an Early Warning of More Serious Diseases?
Lamb DJ.
europepmc +1 more source
Down-regulation of CatSper 1 and CatSper 2 genes by lead and mercury [PDF]
In the study of the expression of CatSper genes, consideration of the effects of environmental metal toxicity is very important. Therefore, in this study, the effects of lead acetate and mercury chloride exposure on expression of CatSper genes, sperm ...
Mostafa Peyvandi +2 more
exaly +5 more sources
The CatSper channel modulates boar sperm motility during capacitation
The cation channel of sperm (CatSper) comprises four transmembrane subunits specifically expressed in human, equine, murine and ovine spermatozoa, apparently implicated in capacitation, hyperactivation and acrosome exocytosis.
Alejandro Vicente-Carrillo +2 more
exaly +6 more sources
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CatSper Calcium Channels: 20 Years On
Physiology, 2023The flagellar-specific Ca2+channel CatSper is the predominant Ca2+entry site in mammalian sperm. CatSper-mediated Ca2+signaling affects nearly every event that regulates sperm to acquire fertilizing capability. In this review, we summarize some of the main findings from 20 years of CatSper research and highlight recent progress and prospects.
Jae Yeon Hwang, Jean-Ju Chung
exaly +3 more sources
A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking [PDF]
Calcium signaling is critical for successful fertilization. In spermatozoa, calcium influx into the sperm flagella mediated by the sperm-specific CatSper calcium channel is necessary for hyperactivated motility and male fertility.
Xiaofang Huang +2 more
exaly +2 more sources
Down-regulation of CatSper 1 and CatSper 2 genes by methamphetamine
Toxin Reviews, 2021Methamphetamine (METH) is a strong central nervous system stimulant that has toxic effects on the reproductive system.
Somaieh Mansouri +3 more
openaire +1 more source
Regulation of the sperm calcium channel CatSper by endogenous steroids and plant triterpenoids [PDF]
Significance The calcium channel of sperm—CatSper—is vital for male fertility. CatSper is activated by the hormone progesterone, but its pharmacological profile is not well studied.
Nadja Mannowetz +2 more
exaly +2 more sources

