Results 161 to 170 of about 1,915 (186)
Some of the next articles are maybe not open access.
A bioinformatics analysis of the CatSper channel in the class Actinopterygii
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2022The regulation of sperm motility is controlled by several variables, including mainly ion concentrations. In fish, Ca2+ concentrations play an important role in the regulation of sperm motility, and several reports highlight the importance of certain Ca2+ channels in the regulation of this cell function. CatSper is a calcium channel scarcely studied in
Jorge F, Beltrán +7 more
openaire +2 more sources
Regulation of the sperm calcium channel CatSper by endogenous steroids and plant triterpenoids [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance The calcium channel of sperm—CatSper—is vital for male fertility. CatSper is activated by the hormone progesterone, but its pharmacological profile is not well studied.
Polina Lishko +2 more
exaly +2 more sources
Science's STKE, 2001
Sperm undergo a process called capacitance, part of which involves increasing their motility in the female reproductive tract. Ren et al. have found and characterized a new Ca 2+ channel expressed in sperm tails, termed CatSper, that is required for sperm motility and male fertility. CatSper
openaire +2 more sources
Sperm undergo a process called capacitance, part of which involves increasing their motility in the female reproductive tract. Ren et al. have found and characterized a new Ca 2+ channel expressed in sperm tails, termed CatSper, that is required for sperm motility and male fertility. CatSper
openaire +2 more sources
2013
In 2001, two groups independently reported different components of a novel Ca2+ channel named CatSper, which is expressed only in the testis and localized in the sperm flagellum. Now, we know that CatSper is a sperm-specific Ca2+ channel composed of four distinct pore-forming subunits accompanied with, at least, three auxiliary subunits. Although there
Takuya Nishigaki +2 more
openaire +1 more source
In 2001, two groups independently reported different components of a novel Ca2+ channel named CatSper, which is expressed only in the testis and localized in the sperm flagellum. Now, we know that CatSper is a sperm-specific Ca2+ channel composed of four distinct pore-forming subunits accompanied with, at least, three auxiliary subunits. Although there
Takuya Nishigaki +2 more
openaire +1 more source
CatSper genes and their role in male infertility: A review
SKUAST Journal of Research, 2022Unexplained infertility is a grave concern in animals as well as humans. In animals, infertility causes huge economic losses. In humans, it accounts for 1020% of cases with overall male infertility accounting for ~30–50% of all infertility cases. Among other factors, genetic defects also cause infertility in a significant proportion of infertile males.
Syed Shanaz +6 more
openaire +1 more source
Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm
Reproduction, 2021Abstract Ca2+ signalling controls human sperm functions necessary for successful fertilization. Multiple endocrine-disrupting chemicals have been found to activate the CatSper Ca2+ channel and thereby interfering with Ca2+ signalling in human sperm. Finasteride is prescribed to men in the fertile age to treat hair loss and its use has
Michala Rosa Birch +3 more
openaire +3 more sources
2021
Background: CatSper is a multi-subunit sperm-specific calcium channel that mediates the progesterone-induced increase in intracellular calcium. Evidence from CatSper subunit knock-out mouse models implicates it as essential for sperm fertilisation competence.
S. G. Brown +4 more
openaire +1 more source
Background: CatSper is a multi-subunit sperm-specific calcium channel that mediates the progesterone-induced increase in intracellular calcium. Evidence from CatSper subunit knock-out mouse models implicates it as essential for sperm fertilisation competence.
S. G. Brown +4 more
openaire +1 more source
[CatSper and sperm hyperactivation].
Zhonghua nan ke xue = National journal of andrology, 2007Elevation of sperm Ca2+ seems to be responsible for an asymmetric form of motility called hyperactivation, which is first seen near the time of fertilization. CatSper family proteins are putative cation channels expressed exclusively in the membranes of the sperm flagellum.
Li-juan, Kong +2 more
openaire +1 more source
A Model of CatSper Channel Mediated Calcium Dynamics in Mammalian Spermatozoa
Bulletin of Mathematical Biology, 2010CatSpers are calcium (Ca(2+)) channels that are located along the principal piece of mammalian sperm flagella and are directly linked to sperm motility and hyperactivation. It has been observed that Ca(2+) entry through CatSper channels triggers a tail to head Ca(2+) propagation in mouse sperm, as well as a sustained increase of Ca(2+) in the head ...
Olson, Sarah D. +2 more
openaire +3 more sources
Insights into sperm cell motility signaling through sNHE and the CatSpers
Molecular and Cellular Endocrinology, 2006Successful natural reproduction normally requires vigorously motile spermatozoa. Using a signal peptide trapping strategy, we identified two new genes, a putative sperm Na+/H+ exchanger (sNHE) and the putative cation channel CatSper2, with unique and essential roles in sperm motility.
Timothy A, Quill +2 more
openaire +2 more sources