Results 61 to 70 of about 1,076,580 (347)
Sufficient Causes: On Oxygen, Matches, and Fires
Journal of Causal Inference, 2019 We demonstrate how counterfactuals can be used to compute the probability that one event was/is a sufficient cause of another, and how counterfactuals emerge organically from basic scientific knowledge, rather than manipulative experiments.
Pearl Judea
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Decision-theoretic foundations for statistical causality
Journal of Causal Inference, 2021 We develop a mathematical and interpretative foundation for the enterprise of decision-theoretic (DT) statistical causality, which is a straightforward way of representing and addressing causal questions.
Dawid Philip
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Nonparametric inference for interventional effects with multiple mediators
Journal of Causal Inference, 2021 Understanding the pathways whereby an intervention has an effect on an outcome is a common scientific goal. A rich body of literature provides various decompositions of the total intervention effect into pathway-specific effects.
Benkeser David, Ran Jialu
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FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
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Incremental intervention effects in studies with dropout and many timepoints#
Journal of Causal Inference, 2021 Modern longitudinal studies collect feature data at many timepoints, often of the same order of sample size. Such studies are typically affected by dropout and positivity violations.
Kim Kwangho +2 more
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The Causal-Neural Connection: Expressiveness, Learnability, and\n Inference [PDF]
, 2021 Kevin Xia +3 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
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Journal of Causal Inference, 2013 There is an ongoing controversy over whether epidural analgesia for women in labor increases the probability of Caesarean section. Previous research compared results from three methods for estimating the effect of epidural analgesia on the probability of
G. Baker Stuart, S. Lindeman Karen
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