Results 71 to 80 of about 414,150 (267)

A Logical Characterization of Constraint-Based Causal Discovery [PDF]

open access: yes, 2011
We present a novel approach to constraint-based causal discovery, that takes the form of straightforward logical inference, applied to a list of simple, logical statements about causal relations that are derived directly from observed (in)dependencies ...
Claassen, Tom, Heskes, Tom
core   +2 more sources

Behavioural Causal Inference

open access: yesReview of Economic Studies
Abstract When inferring causal effects from correlational data, a common practice by professional researchers but also lay people is to control for potential confounders. Inappropriate controls produce erroneous causal inferences. I model decision-makers (DMs) who use endogenous observational data to learn actions’ causal effect on ...
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Design and Analysis of Experiments in Networks: Reducing Bias from Interference

open access: yesJournal of Causal Inference, 2016
Estimating the effects of interventions in networks is complicated due to interference, such that the outcomes for one experimental unit may depend on the treatment assignments of other units.
Eckles Dean, Karrer Brian, Ugander Johan
doaj   +1 more source

Visual Causal Feature Learning [PDF]

open access: yes, 2015
We provide a rigorous definition of the visual cause of a behavior that is broadly applicable to the visually driven behavior in humans, animals, neurons, robots and other perceiving systems. Our framework generalizes standard accounts of causal learning
Chalupka, Krzysztof   +2 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Generalizing Experimental Findings

open access: yesJournal of Causal Inference, 2015
This note examines one of the most crucial questions in causal inference: “How generalizable are randomized clinical trials?” The question has received a formal treatment recently, using a non-parametric setting, and has led to a simple and general ...
Pearl Judea
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Longitudinal Mediation Analysis with Time-varying Mediators and Exposures, with Application to Survival Outcomes

open access: yesJournal of Causal Inference, 2017
1 In this paper, we study the effect of a time-varying exposure mediated by a time-varying intermediate variable. We consider general longitudinal settings, including survival outcomes.
Zheng Wenjing, van der Laan Mark
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy