Results 81 to 90 of about 1,076,580 (347)
Design and Analysis of Experiments in Networks: Reducing Bias from Interference
Journal of Causal Inference, 2016 Estimating the effects of interventions in networks is complicated due to interference, such that the outcomes for one experimental unit may depend on the treatment assignments of other units.
Eckles Dean, Karrer Brian, Ugander Johan
doaj +1 more source
Policy recommendations from causal inference in physics education research [PDF]
, 2021 M. B. Weissman
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Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Generalizing Experimental Findings
Journal of Causal Inference, 2015 This note examines one of the most crucial questions in causal inference: “How generalizable are randomized clinical trials?” The question has received a formal treatment recently, using a non-parametric setting, and has led to a simple and general ...
Pearl Judea
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Journal of Causal Inference, 2017 1 In this paper, we study the effect of a time-varying exposure mediated by a time-varying intermediate variable. We consider general longitudinal settings, including survival outcomes.
Zheng Wenjing, van der Laan Mark
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Data-Adaptive Causal Effects and Superefficiency
Journal of Causal Inference, 2016 Recent approaches in causal inference have proposed estimating average causal effects that are local to some subpopulation, often for reasons of efficiency.
Aronow Peter M.
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Grab the Reins of Crowds: Estimating the Effects of Crowd Movement Guidance Using Causal Inference [PDF]
, 2021 Koh Takeuchi +3 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source