Depressive symptoms mediate the association between sleep disorders and gallstone disease: a causal mediation analysis of NHANES 2017-2020. [PDF]
Hou Y +7 more
europepmc +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Causal Mediation Analysis for the Intergenerational Transmission of Violence Reveals Pathways From Child Maltreatment to Elder Mistreatment. [PDF]
Pickering CEZ +6 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Causal mediation analysis for time-to-event outcomes on the Restricted Mean Survival Time scale: A pseudo-value approach. [PDF]
Chernofsky A, Lok JJ.
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Does the Path From Cigarette Smoking to Suicide Death Go Through the Hospital? A Causal Mediation Analysis in a National Canadian Sample. [PDF]
Balbuena L +4 more
europepmc +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Causal Mediation Analysis of Foodborne <i>Salmonella</i> Outbreaks in the United States: Serotypes and Food Vehicles. [PDF]
Buyrukoğlu G, Moreira J, Topalcengiz Z.
europepmc +1 more source
Biological Age, Chronological Age, and Survival in Pulmonary Fibrosis: A Causal Mediation Analysis. [PDF]
Pugashetti JV +19 more
europepmc +1 more source

