Results 91 to 100 of about 6,601,325 (263)
Exploring the Causal Relationship Between Osteoporosis and Rheumatoid Arthritis: A Bidirectional Mendelian Randomization Study [PDF]
Jie Li, Li Bao, Can Dai, Miao He Department of Orthopedic Surgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, People’s Republic of ChinaCorrespondence: Miao He; Can Dai, Email smallhem@163.com; daican78123@126 ...
Li J, Bao L, Dai C, He M
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Testing causal relationships between energy consumption, real income and prices: evidence from Turkey [PDF]
In this paper, we examine the causal relationships between the changes in energy consumption, real income growth and domestic inflation within the conditions of the Turkish economy.
Levent, Korap
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Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Energy Consumption and Economic Growth in Sweden: A Leveraged Bootstrap Approach, 1965-2000 [PDF]
The causal interaction between energy consumption, real activity and the prices in the Swedish economy is investigated over the period 1965-2000. The leveraged bootstrap simulation technique is used to generate more reliable critical values for tests of ...
Irandoust, M., Hatemi, A.
core
Beyond Covariation: Cues to Causal Structure [PDF]
, 2010 Causal induction has two components: learning about the structure of causal models and learning about causal strength and other quantitative parameters. This chapter argues for several interconnected theses.
Hagmaye, Y +3 more
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Causality Relationship between Real GDP and Electricity Consumption in Romania (2001-2010) [PDF]
After Industrial Revolution, importance of energy in production has increased. As a result of two petroleum crisis, energy was included directly into the production function. While development level of countries has increased, energy consumption has also
Kayhan, Selim +3 more
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生物医学转化Objective This study aims to explore the causal relationship between immune cells and obesity risk using the Mendelian randomization (MR) method. Methods Data sets for 731 types of immune cells and obesity were obtained from the Genome Wide Association ...
Zhu Yun +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source