Results 61 to 70 of about 6,350,077 (307)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Causal relationship between immune cells and obesity risk:Univariate bidirectional and multivariate Mendelian randomization study

生物医学转化
Objective This study aims to explore the causal relationship between immune cells and obesity risk using the Mendelian randomization (MR) method. Methods Data sets for 731 types of immune cells and obesity were obtained from the Genome Wide Association ...
Zhu Yun, Lin Ruifang, Liu Yongjun, Li Ya, Guo Zhihua   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

No Evidence for a Causal Relationship Between Cancers and Parkinson’s Disease

Journal of Parkinson’s Disease, 2021
Background: Epidemiological data suggest that cancer patients have a reduced risk of subsequent Parkinson’s disease (PD) development, but the prevalence of PD in melanoma patients is often reported to be increased.
Konstantin Senkevich, Sara Bandres-Ciga, Eric Yu, Upekha E. Liyanage, , Alastair J Noyce, Ziv Gan-Or   +6 more
doaj   +1 more source

Causal Discovery Toolbox: Uncovering causal relationships in Python.

J. Mach. Learn. Res., 2020
This paper presents a new open source Python framework for causal discovery from observational data and domain background knowledge, aimed at causal graph and causal mechanism modeling. The Cdt package implements an end-to-end approach, recovering the direct dependencies (the skeleton of the causal graph) and the causal relationships between variables.
Kalainathan, Diviyan, Goudet, Olivier, Dutta, Ritik   +2 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Causal Relationship between Emotional Labor Strategies and Teacher Burnout

Acta Paedagogica Vilnensia
This study aims to pinpoint the emotional labor strategy most frequently used by teachers and gender differences identified in the emotional labor strategies.
Ahmad M. Mahasneh, Ahmad M. Gazo
doaj   +1 more source

Causal links between trade, foreign direct investment and economic growth for Bangladesh [PDF]

This study investigates empirically the causal relationship between trade, foreign direct investment (FDI) and economic growth of Bangladesh for the period of 1973 to 2008.
Syed Imran Ali Meerza
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Causal relationship k

International Journal of Mathematics Trends and Technology, 2020
Published by International Journal of Mathematics Trends and Technology (IJMTT) http://www.ijmttjournal.org/archive/ijmtt-v66i10p512 © 2020 by IJMTT Journal Volume-66 Issue-10 Year of Publication ...
openaire   +5 more sources