Results 81 to 90 of about 1,626,990 (326)

Does the IV estimator establish causality? Re-examining Chinese fertility-growth relationship [PDF]

open access: yes
The instrumental variable (IV) estimator in a cross-sectional or panel regression model is often taken to provide valid causal inference from contemporaneous correlations.
Jiaying Gu, Tilak Abeysinghe
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Metabolic score for visceral fat (METS-VF) is associated with arterial stiffness progression in Type 2 diabetes: a retrospective cohort study of China

open access: yesBMC Endocrine Disorders
Background Arterial stiffness is a risk factor for cardiovascular disease (CVD). There is an interaction effect between arterial stiffness and diabetes and may increase the risk of CVD.
Kun Li   +3 more
doaj   +1 more source

Economic growth, electricity consumption and foreign dependence in Italy between 1963 and 2007 [PDF]

open access: yes
The energy sector is assuming an increasing importance in the global economy. As a consequence, there is a vast literature on the causal relation between energy use and others economic variables.
Vecchione, Gaetano
core   +1 more source

Structure and Complexity in Planning with Unary Operators

open access: yes, 2011
Unary operator domains -- i.e., domains in which operators have a single effect -- arise naturally in many control problems. In its most general form, the problem of STRIPS planning in unary operator domains is known to be as hard as the general STRIPS ...
Brafman, R. I., Domshlak, C.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Causality tests between stock market development and economic growth in West African Monetary Union [PDF]

open access: yes
This paper examines the causal relationship between stock market development and economic growth for the West African Monetary Union economy over the last decade or so.
ABOUDOU Maman Tachiwou
core  

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