Results 111 to 120 of about 29,154 (226)
Сell aspects of chronic noninfectious diseases pathogenesis
Атеросклероз, 2014 Caveolae are plasma membrane invaginations of the majority of differentiated cells. They are especially abundant in endothelial cells, adipocytes, muscle cells, and fibroblasts.
Yu P. Nikitin +4 more
doaj
Periodontology 2000, EarlyView.Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad +6 more
wiley +1 more source
Myocardin drives formation of caveolae.
, 2015 Coronary smooth muscle cells, cultured on polycarbonate membranes, were transduced with Ad-CMV-MYOCD or Ad-CMV-null for 96h and prepared for electron microscopy. Left micrographs in panel A show control cells (Ad-CMV-null) where caveolae were rare. Rough
Ola Hansson (88199) +11 more
core +1 more source
TMEM16A channel signalling microdomains in the regulation of vascular function
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
Caveolae : biochemical analysis
, 2004 Caveolae appear in a multitude of processes encompassing growth regulation and trafficking. We demonstrate the abundant presence of ESA/reggie-1/flotillin-2, ATP synthase beta subunit and annexin V in endothelial caveolae by immunopurification of ...
Chatenay-Rivauday, C. +4 more
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Integration of signalling in smooth muscle caveolae [PDF]
, 2010 Caveolae and lipid rafts are plasma membrane microdomains that are considered to play a role in cellular signalling. Caveolins and cavins as well as cholesterol are required for the structure and function of caveolae. The papers summarized in this thesis
Shakirova, Yulia
core
ETX treatment causes caveolae formation.
, 2019 (A) SEM of primary BEC treated with or without 50nM of ETX for 1 hour. White arrows point to apical surface invaginations. (B) Higher magnification of surface invaginations on ETX treated BEC.
Francisco A. Uzal (7841351) +7 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Immunohistochemistry, electrophysiology and pharmacology are useful tools for understanding protein and channel expression and physiological reactions of calcium‐activated chloride channels (CaCCs). Conventional transmission electron microscopy has provided useful 2‐D information on organelle arrangement, localization and ...
Hiromi Tamada
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura +4 more
wiley +1 more source
Caveolae structure and importance in insulin action
, 2004 Type II diabetes is a disease characterized by chronic hyperglycaemia and abnormalities in lipid metabolism that affects approximately 5% of the population in the Western World.
Thyberg, Johan,, Thorn, Hans,
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