Results 121 to 130 of about 29,154 (226)
The Journal of Physiology, EarlyView.Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
The caveolae dress code: structure and signaling
, 2017 International audienceOver the past decade, interest in caveolae biology has peaked. These small bulb-shaped plasma membrane invaginations of 50-80nm diameter present in most cell types have been upgraded from simple membrane structures to a more complex
Melissa Dewulf +9 more
core +1 more source
Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell +3 more
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
, 2007 Endothelial nitric oxide synthase (eNOS) plays a crucial role in the regulation of a variety of cardiovascular functions. Many studies have shown that dietary n-3 polyunsaturated fatty acids (PUFAs) have beneficial effects on coronary atherosclerosis ...
Li, Ning +10 more
core +1 more source
Comprehensive Physiology, Volume 16, Issue 5, October 2026.Pulmonary hypertension is driven by dynamic crosstalk beyond the physical connection between the heart and lung, involving neurohormonal systems, immune pathways, and peripheral organs. This review highlights how multisystem signaling contributes to disease progression and may reveal new diagnostic and therapeutic targets.
Alejandro A. Vega +4 more
wiley +1 more source
Caveolae: biochemical analysis [PDF]
, 2018 aveolae appear in a multitude of processes encompassing growth regulation andtrafficking. We demonstrate the abundant presence of ESA/reggie-1/flotillin-2,ATP synthase β subunit and annexin V in endothelial caveolae byimmunopurification of caveolae from ...
Cakar, Z. +4 more
core
Role of Caveolae in Membrane Tension
, 2014 Caveolae, the characteristic plasma membrane invaginations present inmany cells, have been associated with numerous functions that still remaindebated.
Darius Vasco Koester (479063)
core +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.Microplastics and nanoplastics (MPs/NPs) are emerging environmental neurotoxicants capable of accumulating in the human brain through blood‐brain barrier transcytosis and olfactory transport pathways. Once within the central nervous system, MPs/NPs trigger interconnected mechanisms including NLRP3 inflammasome activation, oxidative stress ...
Alfi Sophian, Asmariani, Erika Ismayani
wiley +1 more source
Silver Nanoparticles (AgNPs) Uptake by Caveolae-Dependent Endocytosis is Responsible for Their Selective Effect Towards Castration Resistant Prostate Cancer [PDF]
Mariana Morais,1,2 Francisca Dias,1 Patrícia Figueiredo,3 Inês Tavares,1,2 Carla Escudeiro,4,5 Manuel R Teixeira,2,4,5 Alexandra Teixeira,6 Johnny Lisboa,6 Kirsi S Mikkonen,3,7 Ana L Teixeira,1 Rui Medeiros1,2,8– 10 1Molecular Oncology and Viral ...
Tavares I +10 more
core