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Science, 2001
Many mammalian cells have indentations in the plasma membrane called caveolae, but exactly what these flask-shaped pits do remains unclear. In a Perspective, Parton discusses the characteristics of caveolin-1-deficient mice that lack caveolae ( Drab et al.).
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Many mammalian cells have indentations in the plasma membrane called caveolae, but exactly what these flask-shaped pits do remains unclear. In a Perspective, Parton discusses the characteristics of caveolin-1-deficient mice that lack caveolae ( Drab et al.).
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Involvement of caveolae and caveolae-like domains in signalling, cell survival and angiogenesis
Cellular Signalling, 2002Caveolae, the flask-shaped membrane invaginations abundant in endothelial cells, have acquired a prominent role in signal transduction. Evidence, that events occurring in caveolae participate in cell survival and angiogenesis, has been recently substantiated by the identification of two novel caveolar constituents: prostacyclin synthase (PGIS) and the ...
MASSIMINO ML +4 more
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Caveolae and the Regulation of Endocytosis
2012Although clathrin-mediated endocytosis constitutes the main pathway for internalization of extracellular ligands and plasma membrane components it has generally been accepted that other uptake mechanisms-caveolae-mediated and noncaveolar raft-dependent endocytosis-also exist.
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Trends in Microbiology, 2001
A recent study 1xCaveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Pelkmans, L. et al. Nat. Cell Biol. 2001; 3: 473–483Crossref | PubMed | Scopus (845)See all References1 on the entry of Simian virus 40 (SV40) into cells has revealed a novel pathway for endocytosis.
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A recent study 1xCaveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Pelkmans, L. et al. Nat. Cell Biol. 2001; 3: 473–483Crossref | PubMed | Scopus (845)See all References1 on the entry of Simian virus 40 (SV40) into cells has revealed a novel pathway for endocytosis.
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Cell biology of caveolae and caveolin
Advanced Drug Delivery Reviews, 2001Originally described in the 1950s caveolae are morphologically identifiable as small omega-shaped plasma membrane invaginations present in most cell types. Caveolae are particularly abundant in adipocytes, fibroblasts, type 1 pneumocytes, endothelial and epithelial cells as well as in smooth and striated muscle cells.
Élise Roussel +3 more
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Atherosclerosis, Caveolae and Caveolin-1
2012Atherosclerosis is a disease of the blood vessel characterized by the development of an arterial occlusion containing lipid and cellular deposits. Caveolae are 50-100 nm cell surface plasma membrane invaginations that are believed to play an important role in the regulation of cellular signaling and transport of molecules among others. These organelles
Pavlides, Stephanos +4 more
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Porin is present in caveolae and caveolae related domains
1999IF: 7 ...
BATHORI G. +9 more
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LDL receptors, caveolae and cholesterol in endothelial dysfunction: oxLDLs accomplices or victims?
British Journal of Pharmacology, 2021Francesca Luchetti +2 more
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