Results 11 to 20 of about 29,727,572 (264)

Caveolin-1 in renal disease [PDF]

Scientific Journal of Genetics and Gene Therapy, 2018
Caveolin-1 is the essential structural formation for lipid raft formation. It has been ascribed to several disease processes in humans due to its ubiquitous distribution.
Chand, Sourabh, Sourabh Chand, Chand Sourabh   +2 more
core   +9 more sources

Caveolin-1–eNOS Signaling Promotes p190RhoGAP-A Nitration and Endothelial Permeability [PDF]

, 2011
Endothelial barrier function is regulated by adherens junctions (AJs) and caveolae-mediated transcellular pathways. The opening of AJs that is observed in caveolin-1-/- (Cav-1-/-) endothelium suggests that Cav-1 is necessary for AJ assembly or ...
Yulia A. Komarova (7945946), Xiaopei Gao (183926), Viktor Brovkovych (7945949), Johnson Rajasingh (347727), Stephen M. Vogel (7945658), Asrar B. Malik (183932), M. Rizwan Siddiqui (7945943), You-Yang Zhao (298133), Marcelo G. Bonini (7921832)   +8 more
core   +7 more sources

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]

, 2013
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
Ivana Hitkova (401838), Ivana Hitkova, Matthias P. A. Ebert, Florian Anderl (183670), Thomas Kirchner (109827), Matthias P A Ebert, Roland M Schmid, Schmid, Roland M., Thomas Kirchner, Claus Schäfer, Roger Vogelmann (358771), Markus Gerhard (183676), Florian Anderl, Elke Burgermeister, Yuan, Gang, Simone Reu, Christoph Röcken (170345), Roland M. Schmid (130086), Ebert, Matthias P. A., Christoph Röcken, Reu, Simone, Schäfer, Claus, Gang Yuan, Vogelmann, Roger, Claus Schäfer (401841), Hitkova, Ivana, Anderl, Florian, Markus Gerhard, Roger Vogelmann, Simone Reu (401840), Röcken, Christoph, Gang Yuan (401839), Matthias P. A. Ebert (250492), Roland M. Schmid, Elke Burgermeister (401842), Kirchner, Thomas, Burgermeister, Elke, Gerhard, Markus   +37 more
core   +2 more sources

Niemann-Pick C1 protein regulates cholesterol transport to the trans-Golgi network and plasma membrane caveolae

Journal of Lipid Research, 2002
The Niemann-Pick C1 (NPC1) protein regulates cholesterol transport from late endosomes-lysosomes to other intracellular compartments. In this article, cholesterol transport to caveolin-1 and caveolin-2 containing compartments, such as the trans-Golgi ...
William S. Garver, Kumar Krishnan, Jayme R. Gallagos, Makoto Michikawa, Gordon A. Francis, Randall A. Heidenreich   +5 more
doaj   +1 more source

Caveolin-1 single nucleotide polymorphism in antineutrophil cytoplasmic antibody associated vasculitis

, 2013
Objective:Immunosuppression is cornerstone treatment of antineutrophil cytoplasmic antibody associated vasculitis (AAV) but is later complicated by infection, cancer, cardiovascular and chronic kidney disease.
Matthew Simmonds (17167288), R. Borrows (17196991), P. Hewins (17197171), A. P. Maxwell (8964656), S. Chand (17196994), M. Hilhorst (17197168), S. Smith (2840546), A. J. McKnight (10735389), L. Harper (13233267), L. Kamesh (17197165), J. U. Holle (17197159), S. Wieczorek (17197174), J. Willem Cohen Tervaert (17197162)   +12 more
core   +5 more sources

Caveolin-1 expression is elevated in claudin-low mammary tumor cells

Cancer Cell International, 2012
Background Caveolin-1 is a scaffolding protein found in plasma membrane invaginations known as caveolae. Caveolin-1 can regulate a number of intracellular processes such as signal transduction, cholesterol metabolism and vesicular transport. With respect
Thompson Devan E, Siwicky Megan D, Moorehead Roger A   +2 more
doaj   +1 more source

Caveolin-1 Signaling in Lung Fibrosis [PDF]

The Open Rheumatology Journal, 2012
Caveolin-1 is a master regulator of several signaling cascades because it is able to bind to and thereby inhibit members of a variety of kinase families. While associated with caveolae and involved in their generation, caveolin-1 is also present at other sites.
Tourkina, Elena, Hoffman, Stanley
openaire   +2 more sources

Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]

, 2014
Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Bieneck, S, Muñoz, N, Quest, AF, Bennett, DC, Silva, V, Sviderskayae, Elena V., Lobos González, Lorena, Muñoz, Nicolás, Fernandez, JG, Silva, Verónica, Hossain, Mehnaz, Bennett, Dorothy C., Fernández Ruiz, Jaime Gonzalo, Quest, Andrew F. G., Burzio, V, Leyton, L, Quest, Andrew F.G., Lobos-Gonzalez, L, Bieneck, Simone, Sviderskaya, EV, Burzioc, Verónica, Aguilar Guzmán, Lorena, Hossain, M, Aguilar Guzmán, Lorena Andrea, Aguilar-Guzmán, L, Leyton Campos, Lisette   +25 more
core   +1 more source

Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress .pdf

, 2023
Caveolin-1 precludes stress-induced protein kinase A-dependent remodelling of endoplasmic reticulum–mitochondria communication.
Beverly Rothermel (16463091)
core   +1 more source

Prognostic significance of epithelial/stromal caveolin‐1 expression in prostatic hyperplasia, high grade prostatic intraepithelial hyperplasia and prostatic carcinoma and its correlation with microvessel density

Journal of the Egyptian National Cancer Institute, 2017
Caveolin-1 may play a role in cancer development and progression. The aim was to record the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high grade prostatic intraepithelial neoplasia (HGPIN) and prostatic carcinoma ...
Dareen A. Mohammed, Duaa S. Helal
doaj   +1 more source