Results 31 to 40 of about 29,727,572 (264)
Journal of Lipid Research, 2010 Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin +12 more
doaj +1 more source
SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes. [PDF]
PLoS ONE, 2014 Reactive oxygen species (ROS) regulate diverse cellular functions by triggering signal transduction events, such as Src and mitogen-activated protein (MAP) kinases.
Ara Jo +6 more
doaj +1 more source
Theoretical model for the formation of caveolae and similar membrane invaginations [PDF]
, 2004 We study a physical model for the formation of bud-like invaginations on fluid lipid membranes under tension, and apply this model to caveolae formation.
Turner, Matthew S. +2 more
core +1 more source
Caveolin-1 expression in benign and malignant lesions of the breast
World Journal of Surgical Oncology, 2007 Background Caveolin-1 is thought to have an important impact on both signal transduction and mediation of intracellular processes. Furthermore, it has been suggested that Caveolin-1 may contribute to certain steps of carcinogenesis in various types of ...
Kiesel Ludwig +4 more
doaj +1 more source
Association/Dissociation of Caveolin-1 and Nitric Oxide Synthase in Preserving Renal Medulla Function during Hemorrhage and Aging [PDF]
, 2021 Background: Caveolin-1 is a negative regulator of endothelial nitric oxide synthase (eNOS), as its interaction and binding suppress the activityof eNOS by making caveolin–eNOS complex.
Balaszczuk, Ana María +4 more
core +1 more source
Dose-Response, 2020 Objective: The aim of this study was to evaluate the levels of caveolin-1 in thyroid follicular epithelial cells of papillary thyroid cancer, follicular thyroid cancer, and nonmalignant thyroid nodule benign follicular adenoma, as well as to explore the ...
Jingyi Zhang +7 more
doaj +1 more source
Caveolin-1 in Cell Migration and Metastasis
Current Molecular Medicine, 2014 Caveolin-1 is a member of the caveolin family that has been ascribed a dual role in cancer. In early stages of disease the protein functions predominantly as a tumor suppressor, whereas at later stages, caveolin-1 expression is associated with tumor progression and metastasis. Here, some mechanisms associated with caveolin-1-dependent tumor suppression
Nunez-Wehinger, S. +5 more
openaire +4 more sources
Tumor Biology, 2017 Despite the consolidated clinico-pathological correlates of Caveolin 1 expression in non–small cell lung cancer, the available data on the role of Caveolin 1 in relation to proliferation, migration, and metastasis in lung adenocarcinoma cells is still ...
Eleonora Duregon +8 more
doaj +1 more source
Scientific Reports, 2017 Caveolae are abundant flask-shaped invaginations of plasma membranes that buffer membrane tension through their deformation. Few quantitative studies on the deformation of caveolae have been reported.
Masashi Tachikawa +6 more
doaj +1 more source
Caveolin-1 expression in different types of psoriatic lesions: Analysis of 66 cases
Indian Journal of Dermatology, 2014 Background: Caveolin-1 is a key structural and functional protein. Caveolin-1 is known to modulate multiple signal-transducing pathways involved in cell differentiation and proliferation. Psoriasis is viewed as a multifactorial pathology characterized by
Feng Zhang +4 more
doaj +1 more source