Results 31 to 40 of about 33,357 (216)
Caveolin-1 expression in different types of psoriatic lesions: Analysis of 66 cases
Indian Journal of Dermatology, 2014 Background: Caveolin-1 is a key structural and functional protein. Caveolin-1 is known to modulate multiple signal-transducing pathways involved in cell differentiation and proliferation. Psoriasis is viewed as a multifactorial pathology characterized by
Feng Zhang +4 more
doaj +1 more source
Caveolin-1 in Cell Migration and Metastasis
Current Molecular Medicine, 2014 Caveolin-1 is a member of the caveolin family that has been ascribed a dual role in cancer. In early stages of disease the protein functions predominantly as a tumor suppressor, whereas at later stages, caveolin-1 expression is associated with tumor progression and metastasis. Here, some mechanisms associated with caveolin-1-dependent tumor suppression
Nunez-Wehinger, S. +5 more
openaire +4 more sources
Tumor Biology, 2017 Despite the consolidated clinico-pathological correlates of Caveolin 1 expression in non–small cell lung cancer, the available data on the role of Caveolin 1 in relation to proliferation, migration, and metastasis in lung adenocarcinoma cells is still ...
Eleonora Duregon +8 more
doaj +1 more source
Caveolin-1 is involved in fatty infiltration and bone-tendon healing of rotator cuff tear
Molecular Medicine, 2023 Background Caveolin-1 has been predicted, based on RNA transcriptome sequencing, as a key gene in rotator cuff tear (RCT) and it is related to fatty infiltration.
Shanhong Fang +3 more
doaj +1 more source
Caveolin-1 regulates Rac1 activation and rat pulmonary microvascular endothelial hyperpermeability induced by TNF-α. [PDF]
PLoS ONE, 2013 A multiplicity of vital cellular and tissue level functions are controlled by caveolin-1 and it is considered to be an important candidate for targeted therapeutics.
Min Shao +5 more
doaj +1 more source
Role of caveolin-1 in fibrotic diseases
Matrix Biology, 2013 Fibrosis underlies the pathogenesis of numerous diseases and leads to severe damage of vital body organs and, frequently, to death. Better understanding of the mechanisms resulting in fibrosis is essential for developing appropriate treatment solutions and is therefore of upmost importance.
Gvariama, D. +3 more
openaire +5 more sources
BMC Cancer, 2012 Background To understand the molecular mechanisms of caveolin-1 downregulation by hepatitis B virus X protein (HBx). Methods The DNA methylation status of the caveolin-1 promoter was examined by nested methylation-specific PCR of 33 hepatitis B virus ...
Yan Jun +5 more
doaj +1 more source
Canadian Journal of Gastroenterology and Hepatology, 2020 Background. Recently, several studies have demonstrated that caveolin-1 overexpression is involved in apoptosis resistance, angiogenesis, and invasiveness in hepatocellular carcinoma (HCC).
Zhi-Bo Zhang +3 more
doaj +1 more source
Critical Role of Caveolin-1 Loss/Dysfunction in Pulmonary Hypertension
Medical Sciences, 2021 Pulmonary hypertension (PH) is a rare disease with a high morbidity and mortality rate. A number of systemic diseases and genetic mutations are known to lead to PH.
Rajamma Mathew
doaj +1 more source
Dermatologica Sinica, 2018 Background: Caveolin-1 (CAV-1) is a key structural and functional membrane protein that is thought to play a role in controlling cellular proliferation and differentiation. Objective: To study the immunohistochemical expression of caveolin-1 in psoriasis
Shereen Farouk Gheida +2 more
doaj +1 more source