Results 21 to 30 of about 33,357 (216)

Caveolin-1 in Kidney Chronic Antibody-Mediated Rejection: An Integrated Immunohistochemical and Transcriptomic Analysis Based on the Banff Human Organ Transplant (B-HOT) Gene Panel

open access: yesBiomedicines, 2021
Caveolin-1 overexpression has previously been reported as a marker of endothelial injury in kidney chronic antibody-mediated rejection (c-ABMR), but conclusive evidence supporting its use for daily diagnostic practice is missing.
Alessandro Gambella   +10 more
doaj   +1 more source

Glycosphingolipid Mediated Caveolin-1 Oligomerization [PDF]

open access: yesJournal of Glycomics & Lipidomics, 2012
We have previously demonstrated an association between the accumulation of the glycosphingolipid globotriaosylceramide (Gb3) and the loss of high molecular weight oligomers in the aortas of α-galactosidase A-knockout mice, a model of Fabry disease. In the present study the molecular basis for the association between glycosphingolipids and caveolin-1 ...
Liming, Shu, James A, Shayman
openaire   +2 more sources

The purified extract of steamed Panax ginseng protects cardiomyocyte from ischemic injury via caveolin-1 phosphorylation-mediating calcium influx

open access: yesJournal of Ginseng Research, 2023
Background: Caveolin-1, the scaffolding protein of cholesterol-rich invaginations, plays an important role in store-operated Ca2+ influx and its phosphorylation at Tyr14 (p-caveolin-1) is vital to mobilize protection against myocardial ischemia (MI ...
Hai-Xia Li   +9 more
doaj   +1 more source

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects[S]

open access: yesJournal of Lipid Research, 2010
Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin   +12 more
doaj   +1 more source

SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes. [PDF]

open access: yesPLoS ONE, 2014
Reactive oxygen species (ROS) regulate diverse cellular functions by triggering signal transduction events, such as Src and mitogen-activated protein (MAP) kinases.
Ara Jo   +6 more
doaj   +1 more source

Caveolin-1 is an aggresome-inducing protein [PDF]

open access: yesScientific Reports, 2016
AbstractCaveolin-1 (Cav1) drives the formation of flask-shaped membrane invaginations known as caveolae that participate in signaling, clathrin-independent endocytosis and mechanotransduction. Overexpression or mutations of Cav1 can lead to its mistrafficking, including its accumulation in a perinuclear compartment previously identified as the Golgi ...
Ajit Tiwari   +5 more
openaire   +2 more sources

Caveolin-1 expression in benign and malignant lesions of the breast

open access: yesWorld Journal of Surgical Oncology, 2007
Background Caveolin-1 is thought to have an important impact on both signal transduction and mediation of intracellular processes. Furthermore, it has been suggested that Caveolin-1 may contribute to certain steps of carcinogenesis in various types of ...
Kiesel Ludwig   +4 more
doaj   +1 more source

Expression of Caveolin-1 Is Associated With Thyroid Function in Patients With Human Papillary Thyroid Carcinoma

open access: yesDose-Response, 2020
Objective: The aim of this study was to evaluate the levels of caveolin-1 in thyroid follicular epithelial cells of papillary thyroid cancer, follicular thyroid cancer, and nonmalignant thyroid nodule benign follicular adenoma, as well as to explore the ...
Jingyi Zhang   +7 more
doaj   +1 more source

Caveolin-1 Signaling in Lung Fibrosis [PDF]

open access: yesThe Open Rheumatology Journal, 2012
Caveolin-1 is a master regulator of several signaling cascades because it is able to bind to and thereby inhibit members of a variety of kinase families. While associated with caveolae and involved in their generation, caveolin-1 is also present at other sites.
Tourkina, Elena, Hoffman, Stanley
openaire   +2 more sources

Measurement of caveolin-1 densities in the cell membrane for quantification of caveolar deformation after exposure to hypotonic membrane tension

open access: yesScientific Reports, 2017
Caveolae are abundant flask-shaped invaginations of plasma membranes that buffer membrane tension through their deformation. Few quantitative studies on the deformation of caveolae have been reported.
Masashi Tachikawa   +6 more
doaj   +1 more source

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