Results 21 to 30 of about 55,130 (252)

Caveolae/Caveolin-1 Are Important Modulators of Store-Operated Calcium Entry in Hs578/T Breast Cancer Cells

Journal of Pharmacological Sciences, 2008
Caveolin-1 is a principal component of caveolae, invaginations of the plasma membrane that are enriched in cholesterol and sphingolipids. The expression of caveolin-1 has been shown to be tightly correlated to the progression of breast cancer tumors ...
Hua Zhu, Noah Weisleder, Ping Wu, Chuanxi Cai, Jian-wen Chen   +4 more
doaj   +1 more source

The caveolin-1 scaffolding domain peptide decreases phosphatidylglycerol levels and inhibits calcium-induced differentiation in mouse keratinocytes. [PDF]

PLoS ONE, 2013
Phospholipase D2 (PLD2) has been found localized in low-density caveolin-rich membrane microdomains. Our previous study suggested that PLD2 and aquaporin 3 (AQP3) interact in these domains to inhibit keratinocyte proliferation and promote differentiation
Haixia Qin, Wendy B Bollag
doaj   +1 more source

Redox Regulation of Signaling Complex between Caveolin-1 and Neuronal Calcium Sensor Recoverin

Biomolecules, 2022
Caveolin-1 is a cholesterol-binding scaffold protein, which is localized in detergent-resistant membrane (DRM) rafts and interacts with components of signal transduction systems, including visual cascade.
Vasiliy I. Vladimirov, Margarita P. Shchannikova, Alexey V. Baldin, Alexey S. Kazakov, Marina P. Shevelyova, Aliya A. Nazipova, Viktoriia E. Baksheeva, Ekaterina L. Nemashkalova, Anastasia S. Frolova, Natalia K. Tikhomirova, Pavel P. Philippov, Andrey A. Zamyatnin, Sergei E. Permyakov, Dmitry V. Zinchenko, Evgeni Yu. Zernii   +14 more
doaj   +1 more source

Caveolin-1 in Kidney Chronic Antibody-Mediated Rejection: An Integrated Immunohistochemical and Transcriptomic Analysis Based on the Banff Human Organ Transplant (B-HOT) Gene Panel

Biomedicines, 2021
Caveolin-1 overexpression has previously been reported as a marker of endothelial injury in kidney chronic antibody-mediated rejection (c-ABMR), but conclusive evidence supporting its use for daily diagnostic practice is missing.
Alessandro Gambella, Antonella Barreca, Simona Osella-Abate, Emanuel Bottasso, Manuela Maria Giarin, Mauro Papotti, Luigi Biancone, Jasna Metovic, Giammarco Collemi, Paola Cassoni, Luca Bertero   +10 more
doaj   +1 more source

Lifestyle intervention in individuals with impaired glucose regulation affects Caveolin-1 expression and DNA methylation [PDF]

, 2020
© 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impaired ...
Adam, S., Dalton, Caroline, Donn, R.P., Fachim, H.A., Gibson, J.M., Heald, A.H., Malipatil, N., Moreno, G.Y.C., Siddals, K., Soran, H.   +9 more
core   +1 more source

Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]

, 2019
PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ, Hollmann, Markus W, Konkel, Moritz, Oei, Gezina TML, Patel, Hemal H, Preckel, Benedikt, Smit, Kirsten F, Weber, Nina C   +7 more
core   +1 more source

Caveolin-1-dependent and -independent membrane domains [PDF]

Journal of Lipid Research, 2009
Lipid rafts defined as cholesterol- and sphingomyelin-rich domains have been isolated from different cell types that vary greatly in their lipid profiles. Here, we investigated the contribution of the structural protein caveolin-1 (Cav1) to the overall lipid composition and domain abundance in mouse embryonic fibroblasts (MEFs) from wild-type (WT) or ...
Le Lay, Soazig, Li, Qiong, Proschogo, Nicholas, Rodriguez, Macarena, Gunaratnam, Krishanthi, Cartland, Siân, Rentero, Carles, Jessup, Wendy, Mitchell, Todd, Gaus, Katharina   +9 more
openaire   +5 more sources

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects[S]

Journal of Lipid Research, 2010
Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin, Soazig Le Lay, Anita Eberl, Harald C. Köfeler, Ida Chiara Guerrera, Christophe Klein, Xavier Le Liepvre, Françoise Lasnier, Olivier Bourron, Jean-François Gautier, Pascal Ferré, Eric Hajduch, Isabelle Dugail   +12 more
doaj   +1 more source

The purified extract of steamed Panax ginseng protects cardiomyocyte from ischemic injury via caveolin-1 phosphorylation-mediating calcium influx

Journal of Ginseng Research, 2023
Background: Caveolin-1, the scaffolding protein of cholesterol-rich invaginations, plays an important role in store-operated Ca2+ influx and its phosphorylation at Tyr14 (p-caveolin-1) is vital to mobilize protection against myocardial ischemia (MI ...
Hai-Xia Li, Yan Ma, Yu-Xiao Yan, Xin-Ke Zhai, Meng-Yu Xin, Tian Wang, Dong-Cao Xu, Yu-Tong Song, Chun-Dong Song, Cheng-Xue Pan   +9 more
doaj   +1 more source

A New N-terminal Recognition Domain in Caveolin-1 Interacts with Sterol Carrier Protein-2 (SCP-2) [PDF]

, 2007
Although plasma membrane domains, such as caveolae, provide an organizing principle for signaling pathways and cholesterol homeostasis in the cell, relatively little is known regarding specific mechanisms, whereby intracellular lipid-binding proteins are
Ball, Judith M., Hostetler, Heather A., Kier, Ann B., Martin, Gregory G., Mir, Kiran D., Parr, Rebecca D., Schroeder, Friedhelm, Schroeder, Megan E.   +7 more
core   +2 more sources