Results 21 to 30 of about 29,727,572 (264)

The role of caveolin-1 in the biofate and efficacy of anti-tumor drugs and their nano-drug delivery systems

open access: yesActa Pharmaceutica Sinica B, 2021
As one of the most important components of caveolae, caveolin-1 is involved in caveolae-mediated endocytosis and transcytosis pathways, and also plays a role in regulating the cell membrane cholesterol homeostasis and mediating signal transduction.
Canyu Yang   +6 more
doaj   +1 more source

Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1

open access: yesBMC Infectious Diseases, 2004
Background Lipid raft domains form in plasma membranes of eukaryotic cells by the tight packing of glycosphingolipids and cholesterol. Caveolae are invaginated structures that form in lipid raft domains when the protein caveolin-1 is expressed.
Norkin Leonard C   +2 more
doaj   +1 more source

Redox Regulation of Signaling Complex between Caveolin-1 and Neuronal Calcium Sensor Recoverin

open access: yesBiomolecules, 2022
Caveolin-1 is a cholesterol-binding scaffold protein, which is localized in detergent-resistant membrane (DRM) rafts and interacts with components of signal transduction systems, including visual cascade.
Vasiliy I. Vladimirov   +14 more
doaj   +1 more source

Caveolae/Caveolin-1 Are Important Modulators of Store-Operated Calcium Entry in Hs578/T Breast Cancer Cells

open access: yesJournal of Pharmacological Sciences, 2008
Caveolin-1 is a principal component of caveolae, invaginations of the plasma membrane that are enriched in cholesterol and sphingolipids. The expression of caveolin-1 has been shown to be tightly correlated to the progression of breast cancer tumors ...
Hua Zhu   +4 more
doaj   +1 more source

Involvement of caveolin-1 in skin diseases

open access: yesFrontiers in Immunology, 2022
The skin is the outermost layer and largest organ in the human body. Since the skin interfaces with the environment, it has a variety of roles, including providing a protective barrier against external factors, regulating body temperature, and retaining water in the body.
Naoko Takamura, Yukie Yamaguchi
openaire   +3 more sources

The caveolin-1 scaffolding domain peptide decreases phosphatidylglycerol levels and inhibits calcium-induced differentiation in mouse keratinocytes. [PDF]

open access: yesPLoS ONE, 2013
Phospholipase D2 (PLD2) has been found localized in low-density caveolin-rich membrane microdomains. Our previous study suggested that PLD2 and aquaporin 3 (AQP3) interact in these domains to inhibit keratinocyte proliferation and promote differentiation
Haixia Qin, Wendy B Bollag
doaj   +1 more source

Caveolin-1 in Kidney Chronic Antibody-Mediated Rejection: An Integrated Immunohistochemical and Transcriptomic Analysis Based on the Banff Human Organ Transplant (B-HOT) Gene Panel

open access: yesBiomedicines, 2021
Caveolin-1 overexpression has previously been reported as a marker of endothelial injury in kidney chronic antibody-mediated rejection (c-ABMR), but conclusive evidence supporting its use for daily diagnostic practice is missing.
Alessandro Gambella   +10 more
doaj   +1 more source

Glycosphingolipid Mediated Caveolin-1 Oligomerization [PDF]

open access: yesJournal of Glycomics & Lipidomics, 2012
We have previously demonstrated an association between the accumulation of the glycosphingolipid globotriaosylceramide (Gb3) and the loss of high molecular weight oligomers in the aortas of α-galactosidase A-knockout mice, a model of Fabry disease. In the present study the molecular basis for the association between glycosphingolipids and caveolin-1 ...
Liming, Shu, James A, Shayman
openaire   +2 more sources

The purified extract of steamed Panax ginseng protects cardiomyocyte from ischemic injury via caveolin-1 phosphorylation-mediating calcium influx

open access: yesJournal of Ginseng Research, 2023
Background: Caveolin-1, the scaffolding protein of cholesterol-rich invaginations, plays an important role in store-operated Ca2+ influx and its phosphorylation at Tyr14 (p-caveolin-1) is vital to mobilize protection against myocardial ischemia (MI ...
Hai-Xia Li   +9 more
doaj   +1 more source

Increased caveolin-1 in intervertebral disc degeneration facilitates repair [PDF]

open access: yes, 2016
BACKGROUND: Preceding intervertebral disc (IVD) degeneration, the cell phenotype in the nucleus pulposus (NP) shifts from notochordal cells (NCs) to chondrocyte-like cells (CLCs). Microarray analysis showed a correlation between caveolin-1 expression and
Alberto Miranda-Bedate (3525206)   +30 more
core   +2 more sources

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