Results 41 to 50 of about 55,130 (252)

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]

, 2013
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
A Bist, A Lee, A Muller, AB Rogers, AS Day, B Razani, C Pelz, C Wunder, CG Hansen, CH Kuo, CH Lai, CH Lai, Christoph Röcken, Claus Schäfer, CM Rosenberger, D Engel, D Forman, D Makola, DW Zaas, E Burgermeister, E Burgermeister, E Burgermeister, E Prade, E Touati, E Touati, Elke Burgermeister, F Lian, F Sommer, FA Medina, FA Medina, FA Medina, Florian Anderl, FS Machado, G Li, G Soong, Gang Yuan, I Mercier, I Regel, IC Arnold, IC Arnold, IC Arnold, IM Toller, Ivana Hitkova, J Li, J Millan, JC Atherton, JE Crabtree, JG Fox, JH Chidlow Jr, JP Boettcher, JS Low, JW Yam, K Ohnuma, K Simons, K Yuan, KM Bourzac, LJ Thompson, M Beigier-Bompadre, M Gadjeva, M Hatakeyama, M Kurayoshi, M Mohammadi, M Yamaga, Markus Gerhard, Matthias P. A. Ebert, MF Dixon, MJ Zhang, ML Hutton, MM D'Elios, MP Ebert, MP Ebert, MR Amieva, NE van Doorn, OA Senkovich, P Gargalovic, P Kundu, P Lajoie, PU Le, R Palovuori, R Rad, R Tsutsumi, Roger Vogelmann, Roland M. Schmid, S Li, S Moese, S Thomas, Simone Reu, Steven R. Blanke, T Kawazoe, T Tomassian, TH Tsai, Thomas Kirchner, TI Jeon, TM Williams, TM Williams, TY Kim, VM Pietiainen, W Schraw, X Cao, X Xing, Y Churin, Y Mitsuno, Y Yamaoka, YC Liao   +103 more
core   +4 more sources

The Rotavirus Enterotoxin NSP4 Directly Interacts with the Caveolar Structural Protein Caveolin-1 [PDF]

, 2006
Rotavirus nonstructural protein 4 (NSP4) is known to function as an intracellular receptor at the endoplasmic reticulum (ER) critical to viral morphogenesis and is the first characterized viral enterotoxin.
Ball, Judith M., McIntosh, Avery, Mir, Kiran D., Mitchell, DeAnne M., Parr, Rebecca D., Storey, Stephen M., Zhou, Minglong   +6 more
core   +2 more sources

Caveolin-1 is involved in fatty infiltration and bone-tendon healing of rotator cuff tear

Molecular Medicine, 2023
Background Caveolin-1 has been predicted, based on RNA transcriptome sequencing, as a key gene in rotator cuff tear (RCT) and it is related to fatty infiltration.
Shanhong Fang, Mengqiang You, Jie Wei, Peng Chen   +3 more
doaj   +1 more source

Critical Role of Caveolin-1 Loss/Dysfunction in Pulmonary Hypertension

Medical Sciences, 2021
Pulmonary hypertension (PH) is a rare disease with a high morbidity and mortality rate. A number of systemic diseases and genetic mutations are known to lead to PH.
Rajamma Mathew
doaj   +1 more source

Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]

, 2014
Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L, Bennett, DC, Bieneck, S, Burzio, V, Fernandez, JG, Hossain, M, Leyton, L, Lobos-Gonzalez, L, Muñoz, N, Quest, AF, Silva, V, Sviderskaya, EV   +11 more
core   +2 more sources

Hepatitis B virus X protein suppresses caveolin-1 expression in hepatocellular carcinoma by regulating DNA methylation

BMC Cancer, 2012
Background To understand the molecular mechanisms of caveolin-1 downregulation by hepatitis B virus X protein (HBx). Methods The DNA methylation status of the caveolin-1 promoter was examined by nested methylation-specific PCR of 33 hepatitis B virus ...
Yan Jun, Lu Qian, Dong Jiahong, Li Xiaowu, Ma Kuansheng, Cai Lei   +5 more
doaj   +1 more source

Caveolin-1 Knockdown Decreases SMMC7721 Human Hepatocellular Carcinoma Cell Invasiveness by Inhibiting Vascular Endothelial Growth Factor-Induced Angiogenesis

Canadian Journal of Gastroenterology and Hepatology, 2020
Background. Recently, several studies have demonstrated that caveolin-1 overexpression is involved in apoptosis resistance, angiogenesis, and invasiveness in hepatocellular carcinoma (HCC).
Zhi-Bo Zhang, Zheng Shi, Lan-Fang Yang, Hong-Bin Gao   +3 more
doaj   +1 more source

Caveolin-1 expression in hyperproliferative skin disorders: A potential predictive marker of disease severity and progression

Dermatologica Sinica, 2018
Background: Caveolin-1 (CAV-1) is a key structural and functional membrane protein that is thought to play a role in controlling cellular proliferation and differentiation. Objective: To study the immunohistochemical expression of caveolin-1 in psoriasis
Shereen Farouk Gheida, Yomna Mazid El-Hamd Neinaa, Dareen Abd El-Aziz Mohammed   +2 more
doaj   +1 more source

CAVEOLIN-1 in prostate cancer [PDF]

, 2022
High prevalence and mortality of prostate cancer (PCa) is well known global health issue. Ongoing search upon new diagnostic, prognostic and predictive marker is always current. There is need of markers which could identify patients with PCa against benign conditions like prostate hyperplasia (BPH) or inflammation.
Škara, Lucija, Dobrović, Irena, Vrhovec, Borna, Sinčić, Nino, Tomas, Davor, Ulamec, Monika   +5 more
openaire   +2 more sources

Caveolin-1 Dependent Endocytosis Enhances the Chemosensitivity of HER-2 Positive Breast Cancer Cells to Trastuzumab Emtansine (T-DM1).

PLoS ONE, 2015
The humanized monoclonal antibody-drug conjugate trastuzumab emtansine (T-DM1, Kadcyla) has been approved by the U.S. FDA to treat human epidermal growth factor receptor 2 (HER-2)-positive metastatic breast cancer.
Yuan-Chiang Chung, Jang-Fang Kuo, Wan-Chen Wei, King-Jen Chang, Wei-Ting Chao   +4 more
doaj   +1 more source