Results 41 to 50 of about 29,727,572 (264)

Caveolin-1 is an aggresome-inducing protein [PDF]

open access: yesScientific Reports, 2016
AbstractCaveolin-1 (Cav1) drives the formation of flask-shaped membrane invaginations known as caveolae that participate in signaling, clathrin-independent endocytosis and mechanotransduction. Overexpression or mutations of Cav1 can lead to its mistrafficking, including its accumulation in a perinuclear compartment previously identified as the Golgi ...
Ajit Tiwari   +5 more
openaire   +2 more sources

Caveolin-1 is involved in fatty infiltration and bone-tendon healing of rotator cuff tear

open access: yesMolecular Medicine, 2023
Background Caveolin-1 has been predicted, based on RNA transcriptome sequencing, as a key gene in rotator cuff tear (RCT) and it is related to fatty infiltration.
Shanhong Fang   +3 more
doaj   +1 more source

Role of caveolin-1 in fibrotic diseases

open access: yesMatrix Biology, 2013
Fibrosis underlies the pathogenesis of numerous diseases and leads to severe damage of vital body organs and, frequently, to death. Better understanding of the mechanisms resulting in fibrosis is essential for developing appropriate treatment solutions and is therefore of upmost importance.
Gvariama, D.   +3 more
openaire   +5 more sources

Caveolin-1 Knockdown Decreases SMMC7721 Human Hepatocellular Carcinoma Cell Invasiveness by Inhibiting Vascular Endothelial Growth Factor-Induced Angiogenesis

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2020
Background. Recently, several studies have demonstrated that caveolin-1 overexpression is involved in apoptosis resistance, angiogenesis, and invasiveness in hepatocellular carcinoma (HCC).
Zhi-Bo Zhang   +3 more
doaj   +1 more source

Oxldl Upregulates Caveolin-1 Expression in Macrophages: Role for Caveolin- 1 in the Adhesion of Oxldl-Treated Macrophages to Endothelium

open access: yes, 2011
Caveolin-1, a principle component of caveolae, is present in several cell types known to play an important role in the development of atherosclerosis.
吳造中;王淑慧;管奕奕;曾維功;陳明豐;吳建春;陳玉怜   +1 more
core   +1 more source

Hepatitis B virus X protein suppresses caveolin-1 expression in hepatocellular carcinoma by regulating DNA methylation

open access: yesBMC Cancer, 2012
Background To understand the molecular mechanisms of caveolin-1 downregulation by hepatitis B virus X protein (HBx). Methods The DNA methylation status of the caveolin-1 promoter was examined by nested methylation-specific PCR of 33 hepatitis B virus ...
Yan Jun   +5 more
doaj   +1 more source

Caveolin-1 regulates Rac1 activation and rat pulmonary microvascular endothelial hyperpermeability induced by TNF-α. [PDF]

open access: yesPLoS ONE, 2013
A multiplicity of vital cellular and tissue level functions are controlled by caveolin-1 and it is considered to be an important candidate for targeted therapeutics.
Min Shao   +5 more
doaj   +1 more source

Caveolin-1 expression in hyperproliferative skin disorders: A potential predictive marker of disease severity and progression

open access: yesDermatologica Sinica, 2018
Background: Caveolin-1 (CAV-1) is a key structural and functional membrane protein that is thought to play a role in controlling cellular proliferation and differentiation. Objective: To study the immunohistochemical expression of caveolin-1 in psoriasis
Shereen Farouk Gheida   +2 more
doaj   +1 more source

Critical Role of Caveolin-1 Loss/Dysfunction in Pulmonary Hypertension

open access: yesMedical Sciences, 2021
Pulmonary hypertension (PH) is a rare disease with a high morbidity and mortality rate. A number of systemic diseases and genetic mutations are known to lead to PH.
Rajamma Mathew
doaj   +1 more source

Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1-0

open access: yes, 2011
Copyright information:Taken from "Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1"BMC Infectious Diseases 2004;4():23-23.Published online 22 Jul 2004PMCID:PMC497042.Copyright © 2004 Webley et al; licensee BioMed
Leonard C Norkin (4287)   +2 more
core   +1 more source

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