Results 91 to 100 of about 7,336 (225)
Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation [PDF]
Caveolae are specialized lipid rafts that form flask-shaped invaginations of the plasma membrane. They are involved in cell signalling and transport and have been shown critically regulate vascular reactivity and blood pressure. The organization and functions of caveolae are mediated by coat proteins (caveolins) and support or adapter proteins (cavins).
John H, Chidlow, William C, Sessa
openaire +2 more sources
North Cavin Street, Ligonier, Indiana [PDF]
Ligonier was platted in 1835 by Isaac Cavin. It had a large Jewish population which began with the immigration of two men in the early 1850s. The 1980s saw the number of Jewish inhabitants dwindle.
core
Morphology of cavin-1-and CAV1-positive structures in Toxoplasma co-expressors. [PDF]
(A–C) Fluorescence microscopy of transgenic parasites expressing cavin-1-HA and CAV1-YFP showing several cavin-1-and CAV1-labeled vesicles and tubules at the parasite periphery. Anti-HA antibodies were used to detect cavin-1-HA.
Vera Sampels (113283) +5 more
core +1 more source
Cellular spelunking: exploring adipocyte caveolae
It has been known for decades that the adipocyte cell surface is particularly rich in small invaginations we now know to be caveolae. These structures are common to many cell types but are not ubiquitous.
Paul F. Pilch +6 more
doaj +1 more source
Caveolae as Potential Hijackable Gates in Cell Communication
Caveolae are membrane microdomains described in many cell types involved in endocytocis, transcytosis, cell signaling, mechanotransduction, and aging. They are found at the interface with the extracellular environment and are structured by caveolin and ...
Maria Dudãu +10 more
doaj +1 more source
ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1
The receptor tyrosine kinase-like orphan receptor 1 (ROR1) sustains prosurvival signalling directly downstream of the lineage-survival oncogene NKX2-1/TTF-1 in lung adenocarcinoma. Here we report an unanticipated function of this receptor tyrosine kinase
Tomoya Yamaguchi +11 more
semanticscholar +1 more source
Pulmonary hypertension (PH) is a progressive disease associated with poor outcomes. Caveolin-1 (Cav1) and Cavin-1 are components of caveolae, and Cav1 is identified as a related gene of pulmonary arterial hypertension (PAH).
S. Tomita +7 more
semanticscholar +1 more source
Digital speech‐based markers to advance prognosis in Alzheimer's disease
Abstract Validated prognostic tools are essential to advance drug development and clinical care in Alzheimer's disease, particularly as the field shifts toward the prevention of cognitive decline. While progress has been made in developing blood‐based biomarkers for the early detection of amyloid pathology, amyloid positivity alone does not reliably ...
Melissa Lee +6 more
wiley +1 more source
Assessment of caveolar endocytosis by CAV1-and/or cavin-1-expressing parasites. [PDF]
(A) IFA of Toxoplasma coexpressing CAV1-YFP cavin-1-HA immunolabeled with antibodies against HA (cavin-1-HA) and SAG1 (plasma membrane, blue) showing no overlap with the plasma membrane.
Vera Sampels (113283) +5 more
core +1 more source
Geological processes shaping freshwater biodiversity: a synthesis of global evidence
ABSTRACT Recent genomic data highlight the key roles of geological processes in shaping the diversification and biogeography of freshwater lineages. Specifically, physical processes such as tectonic uplift, erosion, glaciation, lake formation, and sea‐level fluctuation contribute extensively to the evolution of biotic diversity within and among ...
Jonathan M. Waters +3 more
wiley +1 more source

