Results 71 to 80 of about 7,336 (225)

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

open access: yeseLife, 2014
In mammalian cells three closely related cavin proteins cooperate with the scaffolding protein caveolin to form membrane invaginations known as caveolae.
Yann Gambin   +18 more
doaj   +1 more source

Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation

open access: yesNature Communications, 2021
Caveolae are spherical nanodomains of the plasma membrane generated by assembly of caveolin and cavin proteins. Here, the authors show that fuzzy electrostatic interactions between caveolin-1 and Cavin1 proteins, combined with membrane lipid interactions,
Vikas A. Tillu   +9 more
doaj   +1 more source

Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis

open access: yesJournal of Biological Chemistry, 2017
Angiogenesis is a highly regulated process for formation of new blood vessels from pre-existing ones. Angiogenesis is dysregulated in various pathologies, including age-related macular degeneration, arthritis, and cancer.
Gandhi T K Boopathy   +8 more
semanticscholar   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

open access: yesBMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang   +13 more
wiley   +1 more source

Axelrodichthys megadromos Cavin, Valentin & Garcia, 2016, sp. nov. [PDF]

open access: yes, 2016
Axelrodichthys megadromos sp. nov. (Figs. 2 and 3) Etymology. From the greek MέƳaς, megas, large and dRόM Ο ς, dromos, driveway. The specific epithet emphasizes the arrival of this taxon from Gondwana probably by dispersal during the ...
Xavier Valentin   +2 more
core   +1 more source

Evaluation of Deviation‐Type Indices for the Joint Selection of Yield and Seed Composition Traits in Soybean (Glycine max (L.) Merr.)

open access: yesPlant Breeding, EarlyView.
ABSTRACT Seed yield and composition are major targets in soybean (Glycine max (L.) Merr.) breeding programmes, but simultaneous improvement is constrained by unfavourable correlations among target traits. In this study, we evaluated the potential of different selection indices to simultaneously improve seed yield and quality traits in soybean.
Vincent Braun   +5 more
wiley   +1 more source

Structural Insights into the Organization of the Cavin Membrane Coat Complex

open access: yesDevelopmental Cell, 2014
Caveolae are cell-surface membrane invaginations that play critical roles in cellular processes including signaling and membrane homeostasis. The cavin proteins, in cooperation with caveolins, are essential for caveola formation. Here we show that a minimal N-terminal domain of the cavins, termed HR1, is required and sufficient for their homo- and ...
Kovtun, Oleksiy   +13 more
openaire   +5 more sources

Cavin 1 and cavin 2 roles on adipocyte cell function [PDF]

open access: yes, 2011
Dissertação para obtenção do Grau de Mestre em Genética Molecular e BiomedicinaCaveolae are a specialized type of lipid rafts found in numerous cell types.
Simões, Francisco Manuel de Carvalho
core  

IGF1induces PTRF/Cavin and Cav-1 internalization. [PDF]

open access: yes, 2013
HaCat cells were treated with IGF1 (10 nM) for 5 min, fixed in 4% formaldehyde, permeabilized with Methanol at −20°C, labeled with (A) a rabbit anti-PTRF/Cavin (red) and a mouse anti-Cav-1 (green), or (B) a mouse anti-IGF-IR (green) and a rabbit anti-Cav-
Mario Passalacqua (253746)   +7 more
core   +1 more source

150 million years of freshwater fish biogeography: vicariance or dispersal? [PDF]

open access: yesResearch & Knowledge, 2017
Freshwater fishes are supposedly good case studies to test palaeobiogeographical models because they are attached to land masses, at least primary freshwater fishes, which are unable to cross marine barriers.
Lionel Cavin
doaj   +1 more source

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