Results 51 to 60 of about 7,336 (225)
SnapShot: Caveolae, Caveolins, and Cavins
Cell, 2013 Caveolae, submicroscopic bulb-shaped plasma membrane pits, are an abundant feature of many mammalian cells (Parton and del Pozo, 2013). Caveolae and the major proteins of caveolae, caveolins (Rothberg et al., 1992), and cavins (Hill et al., 2008), are linked to a number of human diseases such as muscular dystrophy, cardiomyopathy, and lipodys -trophy ...
Ariotti, Nicholas, Parton Robert G.
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Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. [PDF]
PLoS ONE, 2014 Caveolae are omega-shaped plasma membrane micro-domains that are abundant in cells of the vascular system. Formation of caveolae depends on caveolin-1 and cavin-1 and lack of either protein leads to loss of caveolae.
Karl Swärd +2 more
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JID Innovations, 2023 Hidradenitis suppurativa (HS) is a chronic, inflammatory skin condition. HS disease management has proven difficult owing to an insufficient understanding of the immunological processes that drive its pathogenesis. We have demonstrated that misregulation
Neil Seth +4 more
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Journal of Extracellular Vesicles, 2014 Background: Tumour-derived extracellular vesicles (EVs) play a role in tumour progression; however, the spectrum of molecular mechanisms regulating EV secretion and cargo selection remain to be fully elucidated.
Kerry L. Inder +11 more
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Fatal cardiac arrhythmia and long-QT syndrome in a new form of congenital generalized lipodystrophy with muscle rippling (CGL4) due to PTRF-CAVIN mutations. [PDF]
PLoS Genetics, 2010 We investigated eight families with a novel subtype of congenital generalized lipodystrophy (CGL4) of whom five members had died from sudden cardiac death during their teenage years. ECG studies revealed features of long-QT syndrome, bradycardia, as well
Anna Rajab +12 more
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Susan Cavin Papers, 1971-1991 [PDF]
, 2008 The Susan Cavin papers can be divided into three main groups; first, those items relating to Cavin's activities as a scholar, teacher, and activist in the Rutgers Community.
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Introduction of caveolae structural proteins into the protozoan Toxoplasma results in the formation of heterologous caveolae but not caveolar endocytosis. [PDF]
PLoS ONE, 2012 Present on the plasma membrane of most metazoans, caveolae are specialized microdomains implicated in several endocytic and trafficking mechanisms. Caveolins and the more recently discovered cavins are the major protein components of caveolae.
Bao Lige +5 more
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Pleiotropic Effects of Cavin-1 Deficiency on Lipid Metabolism [PDF]
Journal of Biological Chemistry, 2014 Mice and humans lacking caveolae due to gene knock-out or inactivating mutations of cavin-1/PTRF have numerous pathologies including markedly aberrant fuel metabolism, lipodystrophy, and muscular dystrophy. We characterized the physiologic/metabolic profile of cavin-1 knock-out mice and determined that they were lean because of reduced white adipose ...
Shi-Ying, Ding +5 more
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Foreyia Cavin, Mennecart, Obrist, Costeur & Furrer, 2017, gen. nov. [PDF]
, 2017 Foreyia gen. nov. Diagnosis Latimeriid coelacanth with dermal bones covered with numerous large tubercles; hypertrophied otico-occipital portion of skull; fusion of postparietal, supratemporal and extrascapular in postparietal shield, which forms a ...
Loïc Costeur +4 more
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