Results 61 to 70 of about 5,482 (203)
Cellular spelunking: exploring adipocyte caveolae
It has been known for decades that the adipocyte cell surface is particularly rich in small invaginations we now know to be caveolae. These structures are common to many cell types but are not ubiquitous.
Paul F. Pilch +6 more
doaj +1 more source
Abstract The frequency and severity of droughts are increasing in grasslands globally. Forecasting changes in community composition is challenging due to the direct and indirect effects of drought as well as varied species ecologies. Rare species are predicted to be more susceptible to perturbations, but extreme drought may also disproportionately ...
Carmen R. E. Watkins +15 more
wiley +1 more source
PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function [PDF]
Caveolae are abundant cell-surface organelles involved in lipid regulation and endocytosis. We used comparative proteomics to identify PTRF (also called Cav-p60, Cavin) as a putative caveolar coat protein. PTRF-Cavin selectively associates with mature caveolae at the plasma membrane but not Golgi-localized caveolin.
Hill, M. M. +11 more
openaire +5 more sources
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche +9 more
wiley +1 more source
Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation [PDF]
Caveolae are specialized lipid rafts that form flask-shaped invaginations of the plasma membrane. They are involved in cell signalling and transport and have been shown critically regulate vascular reactivity and blood pressure. The organization and functions of caveolae are mediated by coat proteins (caveolins) and support or adapter proteins (cavins).
John H, Chidlow, William C, Sessa
openaire +2 more sources
Caveolins/caveolae protect adipocytes from fatty acid-mediated lipotoxicity
Mice and humans lacking functional caveolae are dyslipidemic and have reduced fat stores and smaller fat cells. To test the role of caveolins/caveolae in maintaining lipid stores and adipocyte integrity, we compared lipolysis in caveolin-1 (Cav1)-null ...
Tova Meshulam +4 more
doaj +1 more source
Caveolae as Potential Hijackable Gates in Cell Communication
Caveolae are membrane microdomains described in many cell types involved in endocytocis, transcytosis, cell signaling, mechanotransduction, and aging. They are found at the interface with the extracellular environment and are structured by caveolin and ...
Maria Dudãu +10 more
doaj +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
The Susan Cavin papers can be divided into three main groups; first, those items relating to Cavin's activities as a scholar, teacher, and activist in the Rutgers Community.
core +1 more source

