Results 61 to 70 of about 7,336 (225)

Generation of Cavin-3 knockout mouse. [PDF]

open access: yes, 2014
Cavin-3 knockout mice were generated as described in “Method”. A. PCR genotyping was performed by using primers against LacZ and Cavin-3. B. Adipose tissue lysates (10 µg) from wild type (W), heterozygous (H) and knockout (K) mouse were separated by SDS ...
Benjamin J. Nichols (450880)   +4 more
core   +1 more source

Cavin-1 regulates cholesterol distribution and Cdc42 activity. [PDF]

open access: yes, 2014
(A) Filipin labeling was performed for Cavin-1-GFP-expressing CAV1−/− MEFs, and for quantification average fluorescence intensity measured from 40–50 transfected cells was normalized to untransfected cells.
Katharina Gaus (47632)   +10 more
core   +1 more source

Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis.

open access: yesPLoS Biology, 2014
Several studies have suggested crosstalk between different clathrin-independent endocytic pathways. However, the molecular mechanisms and functional relevance of these interactions are unclear.
Natasha Chaudhary   +10 more
doaj   +1 more source

Intermittent Hypoxia Mediates Caveolae Disassembly That Parallels Insulin Resistance Development

open access: yesFrontiers in Physiology, 2020
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders.
Maider Varela-Guruceaga   +7 more
doaj   +1 more source

Molecular composition and ultrastructure of the caveolar coat complex.

open access: yesPLoS Biology, 2013
Caveolae are an abundant feature of the plasma membrane of many mammalian cell types, and have key roles in mechano-transduction, metabolic regulation, and vascular permeability.
Alexander Ludwig   +7 more
doaj   +1 more source

Caveolae and Lipid Rafts in Endothelium: Valuable Organelles for Multiple Functions

open access: yesBiomolecules, 2020
Caveolae are flask-shaped invaginations of the plasma membrane found in numerous cell types and are particularly abundant in endothelial cells and adipocytes.
Antonio Filippini, Alessio D’Alessio
doaj   +1 more source

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang   +6 more
wiley   +1 more source

Expression and localization of cavin-1 in Toxoplasma. [PDF]

open access: yes, 2012
(A) Expression of cavin-1-HA by transgenic parasites. Immunoblots of homogenates from wild-type T. gondii (left lane) and Toxoplasma stably expressing cavin-1-HA (right lane) revealed with anti-HA antibodies (α-HA).
Vera Sampels (113283)   +5 more
core   +1 more source

Investigation of Novel Cavin-1/Suppressor of Cytokine Signaling 3 (SOCS3) Interactions by Coimmunoprecipitation, Peptide Pull-Down, and Peptide Array Overlay Approaches.

open access: yesMethods in molecular biology, 2020
The ability of inducible regulator suppressor of cytokine signaling 3 (SOCS3) to inhibit Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling requires interaction with specific cytokine receptors, JAKs, and components of the
Jamie J. L. Williams   +2 more
semanticscholar   +1 more source

Description of large, well‐preserved Enchodus specimens from the Bearpaw Formation of Alberta, Canada

open access: yesThe Anatomical Record, EarlyView.
Abstract Fishes of the genus Enchodus were abundant and cosmopolitan in the Late Cretaceous, but are primarily known from isolated remains in Canada. Four well‐preserved fish skulls were recovered in recent years from ammolite mines sampling the Bearpaw Formation of Southern Alberta, and are here referred to Enchodus petrosus Cope, 1874.
Luke E. Nelson   +2 more
wiley   +1 more source

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