Cavin family proteins and the assembly of caveolae
Journal of Cell Science, 2015 ABSTRACT Caveolae are an abundant feature of the plasma membrane in many cells. Until recently, they were generally considered to be membrane invaginations whose formation primarily driven by integral membrane proteins called caveolins. However, the past decade has seen the emergence of the cavin family of peripheral membrane proteins as
Oleksiy Kovtun +4 more
semanticscholar +7 more sources
Journal of Biological Chemistry, 2022 Caveolae are invaginated membrane domains that provide mechanical strength to cells in addition to being focal points for the localization of signaling molecules. Caveolae are formed through the aggregation of caveolin-1 or -3 (Cav1/3), membrane proteins
Androniqi Qifti +2 more
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Role of Caveolae family-related proteins in the development of breast cancer
Frontiers in Molecular Biosciences, 2023 Breast cancer has become the most significant malignant tumor threatening women’s lives. Caveolae are concave pits formed by invagination of the plasma membrane that participate in many biological functions of the cell membrane, such as endocytosis, cell
Qinyu Han +4 more
doaj +1 more source
Immune-Mediated Rippling Muscle Disease Associated With Thymoma and Anti-MURC/Cavin-4 Autoantibodies
Neurology: Neuroimmunology & Neuroinflammation, 2022 Objectives Rippling muscle disease (RMD) is characterized by muscle stiffness, muscle hypertrophy, and rippling muscle induced by stretching or percussion.
J. Svahn +20 more
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Hypoxia Inhibits Cavin-1 and Cavin-2 Expression and Down-Regulates Caveolae in Adipocytes [PDF]
Endocrinology, 2015 AbstractDuring obesity, a hypoxic state develops within the adipose tissue, resulting in insulin resistance. To understand the underlying mechanism, we analyzed the involvement of caveolae because they play a crucial role in the activation of insulin receptors.
Regazzetti, Claire +14 more
openaire +2 more sources
Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1. [PDF]
PLoS ONE, 2012 Caveolin-1 and caveolae are differentially polarized in migrating cells in various models, and caveolin-1 expression has been shown to quantitatively modulate cell migration.
Michelle M Hill +13 more
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Interview with Amanda Cavin - OH 650 [PDF]
, 2021 This interview was conducted for the as part of the 20th Anniversary of the September 11th Terrorist Attacks on the United States. This effort was to produce a history of the university’s, as well as the community’s, response in the days and weeks ...
Cavin, Amanda
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MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line. [PDF]
PLoS ONE, 2015 The purpose of this study was to investigate whether MURC/cavin-4, a plasma membrane and Z-line associated protein exhibiting an overlapping distribution with Caveolin-3 (Cav-3) in heart and muscle tissues, may be expressed and play a role in ...
Fiorella Faggi +15 more
doaj +1 more source
Cavin 2 and cavin 3 form distinct subcomplexes with cavin 1 and caveolin 1. [PDF]
, 2013 (A) Gradient fractions (10–40% sucrose) of non-cross-linked and detergent solubilised (1% Triton X-100) HeLa cell extracts were analysed by Western blotting.
Gillian Howard (450875) +7 more
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Cavin-1 and Cavin-3, but not Cavin-2 and Cavin-4 negatively regulate CLIC endocytosis. [PDF]
, 2014 (A) CAV1−/− MEFs were transiently transfected with pIRES-GFP, pIRES-Cavin-1, pIRES-Cavin-2, pIRES-Cavin-3, and pIRES-Cavin-4 respectively and internalization assay was performed with anti-CD44 mAb and Tfn-647 for 2 min at 37°C.
Katharina Gaus (47632) +10 more
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