Unraveling calcium dysregulation and autoimmunity in immune mediated rippling muscle disease [PDF]
Acta Neuropathologica CommunicationsRippling Muscle Disease (RMD) is a rare skeletal myopathy characterized by abnormal muscular excitability manifesting with wave-like muscle contractions and percussion-induced muscle mounding.
Samir R. Nath +10 more
doaj +2 more sources
Pre‐drought Conservative Xylem Hydraulic Architecture Is Associated With Enhanced Recovery From the 1976 Drought in European Beech (Fagus sylvatica L.) [PDF]
Plant Cell EnvironPlant, Cell &Environment, Volume 49, Issue 9, Page 7215-7218, September 2026.
Simon Röder +8 more
wiley +2 more sources
Interview with Amanda Cavin - OH 650 [PDF]
, 2021 This interview was conducted for the as part of the 20th Anniversary of the September 11th Terrorist Attacks on the United States. This effort was to produce a history of the university’s, as well as the community’s, response in the days and weeks ...
Cavin, Amanda
core +1 more source
Hypoxia Inhibits Cavin-1 and Cavin-2 Expression and Down-Regulates Caveolae in Adipocytes [PDF]
Endocrinology, 2015 AbstractDuring obesity, a hypoxic state develops within the adipose tissue, resulting in insulin resistance. To understand the underlying mechanism, we analyzed the involvement of caveolae because they play a crucial role in the activation of insulin receptors.
Regazzetti, Claire +14 more
openaire +2 more sources
MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line. [PDF]
PLoS ONE, 2015 The purpose of this study was to investigate whether MURC/cavin-4, a plasma membrane and Z-line associated protein exhibiting an overlapping distribution with Caveolin-3 (Cav-3) in heart and muscle tissues, may be expressed and play a role in ...
Fiorella Faggi +15 more
doaj +1 more source
Lessons from cavin-1 deficiency [PDF]
Biochemical Society Transactions, 2020 Caveolae have been implicated in a wide range of critical physiological functions. In the past decade, the dominant role of cavin-1 in caveolae formation has been established, and it has been recognized as another master regulator for caveolae biology.
openaire +2 more sources
Cavin-3 dictates the balance between ERK and Akt signaling
eLife, 2013 Cavin-3 is a tumor suppressor protein of unknown function. Using both in vivo and in vitro approaches, we show that cavin-3 dictates the balance between ERK and Akt signaling.
Victor J Hernandez +8 more
doaj +1 more source
Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. [PDF]
PLoS ONE, 2014 Caveolae are omega-shaped plasma membrane micro-domains that are abundant in cells of the vascular system. Formation of caveolae depends on caveolin-1 and cavin-1 and lack of either protein leads to loss of caveolae.
Karl Swärd +2 more
doaj +1 more source
JID Innovations, 2023 Hidradenitis suppurativa (HS) is a chronic, inflammatory skin condition. HS disease management has proven difficult owing to an insufficient understanding of the immunological processes that drive its pathogenesis. We have demonstrated that misregulation
Neil Seth +4 more
doaj +1 more source
SnapShot: Caveolae, Caveolins, and Cavins
Cell, 2013 Caveolae, submicroscopic bulb-shaped plasma membrane pits, are an abundant feature of many mammalian cells (Parton and del Pozo, 2013). Caveolae and the major proteins of caveolae, caveolins (Rothberg et al., 1992), and cavins (Hill et al., 2008), are linked to a number of human diseases such as muscular dystrophy, cardiomyopathy, and lipodys -trophy ...
Ariotti, Nicholas, Parton Robert G.
openaire +5 more sources