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Electrical Stimulation Using a Low-Frequency and Low-Intensity Alternating Current Modulates Type I Procollagen Production and MMP-1 Expression in Dermal Fibroblasts. [PDF]
Ann DermatolKang BM +8 more
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Cavin proteins: New players in the caveolae field
Biochimie, 2011Caveolae are specialized lipid microdomains, forming small invaginations in the plasma membrane, known to be implicated in multiple functions including lipid storage, cell signaling and endocytosis. Formation of these wide flask-shaped invaginations is dependent on the expression of a caveolar coat protein, namely caveolin.
Nolwenn Briand +2 more
exaly +3 more sources
Caveolae-Associated Protein 3 (Cavin-3) Influences Adipogenesis via TACE-Mediated Pref-1 Shedding
International Journal of Molecular Sciences, 2020 Abnormal adipogenesis regulation is accompanied by a variety of metabolic dysfunctions and disorders. Caveolae play an important role in the regulation of fat production, modulated by caveolae-associated proteins (Cavin-1 to 4). Here, we investigated the
Sung Tae Kim, Phil June Park
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Acetylation of Cavin-1 Promotes Lipolysis in White Adipose Tissue [PDF]
Molecular and Cellular Biology, 2017 White adipose tissue (WAT) serves as a reversible energy storage depot in the form of lipids in response to nutritional status. Cavin-1, an essential component in the biogenesis of caveolae, is a positive regulator of lipolysis in adipocytes. However, molecular mechanisms of cavin-1 in the modulation of lipolysis remain poorly understood.
Liang Guo, Xu Wang, Yuan Liu
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Caveolin and cavin family members: Dual roles in cancer
Biochimie, 2014Caveolae are specialized plasma membrane subdomains with distinct lipid and protein compositions, which play an essential role in cell physiology through regulation of trafficking and signaling functions. The structure and functions of caveolae have been shown to require the proteins caveolins.
Reshu Gupta +2 more
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Exploring the caves: cavins, caveolins and caveolae
Trends in Cell Biology, 2010Caveolae are ampullate (flask-shaped) invaginations that are abundant in the plasma membrane of many mammalian cell types. Although caveolae are implicated in a wide range of processes including endothelial transcytosis, lipid homeostasis and cellular signalling, a detailed molecular picture of many aspects of their function has been elusive.
Carsten G, Hansen, Ben J, Nichols
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Focus on the role of Caveolin and Cavin protein families in liposarcoma
Differentiation, 2017The identification of ancillary biomarkers useful to improve diagnosis is a major challenge for adipocytic liposarcoma (LPS), the most common type among soft tissue sarcomas affecting adulthood. Recent findings have reported the expression of some proteins belonging to Caveolin and Cavin families as a critical hallmark distinctive of the least ...
Codenotti, Silvia +3 more
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Characterisation of the cavin proteins role in the circadian rhythm [PDF]
, 2022 Caveolae are nanoscale size invaginations of the plasma membrane identified by their unique flask-shape morphology. They are considered to play an important role in lipid metabolism and provide essential mechanosensing and protective capacity to the membrane. The cytosolic coat composed of the cavin family of proteins, namely Cavin1, Cavin2, Cavin3 and
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Cavin-1: caveolae-dependent signalling and cardiovascular disease
Biochemical Society Transactions, 2014Caveolae are curved lipid raft regions rich in cholesterol and sphingolipids found abundantly in vascular endothelial cells, adipocytes, smooth muscle cells and fibroblasts. They are multifunctional organelles with roles in clathrin-independent endocytosis, cholesterol transport, mechanosensing and signal transduction.
Williams, Jamie J.L., Palmer, Timothy M.
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