Comprehensive analysis of the prognostic and immunological role of cavins in non-small cell lung cancer [PDF]
BMC CancerCaveolae, specialized and dynamic subdomains of the plasma membrane, have a crucial role in diverse cellular functions encompassing endocytosis, signal transduction, mechanosensation, lipid storage, and metabolism. Cavin family proteins are indispensable
Kelin Mou +12 more
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Caveolae, caveolins, cavins, and endothelial cell function: new insights [PDF]
Frontiers in Physiology, 2012 Caveolae are cholesterol and glycosphingolipid-rich flask-shaped invaginations of the plasma membrane which are particularly abundant in vascular endothelium and present in all other cell types of the cardiovascular system, including vascular smooth ...
Grzegorz Sowa
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Cavin gene family and caveolae-related disorders: pathogenetic roles and possible mechanisms [PDF]
Cell Communication and SignalingCavins, in concert with caveolins, orchestrate the formation and function of caveolae—specialized invaginations of the plasma membrane involved in mechanotransduction, lipid homeostasis, and cell signaling. The Cavin family comprises four members: Cavins
Youssef Osman +4 more
doaj +3 more sources
PLoS ONE, 2017 Caveolae are membrane invaginations present at high densities in muscle and fat. Recent work has demonstrated that myocardin family coactivators (MYOCD, MKL1), which are important for contractile differentiation and cell motility, increase caveolin (CAV1,
Sebastian Albinsson +2 more
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Role of Caveolae family-related proteins in the development of breast cancer [PDF]
Frontiers in Molecular Biosciences, 2023 Breast cancer has become the most significant malignant tumor threatening women’s lives. Caveolae are concave pits formed by invagination of the plasma membrane that participate in many biological functions of the cell membrane, such as endocytosis, cell
Shi Qiu, Xiangqi Li
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The molecular organization of differentially curved caveolae indicates bendable structural units at the plasma membrane [PDF]
Nature Communications, 2022 Caveolae are small coated plasma membrane invaginations with diverse functions. Caveolae undergo curvature changes. Yet, it is unclear which proteins regulate this process. To address this gap, we develop a correlative stimulated emission depletion (STED)
Claudia Matthaeus +6 more
doaj +3 more sources
Integrated Bioinformatic Analysis of the Expression and Prognosis of Caveolae-Related Genes in Human Breast Cancer [PDF]
Frontiers in Oncology, 2021 Caveolae-related genes, including CAVs that encodes caveolins and CAVINs that encodes caveolae-associated proteins cavins, have been identified for playing significant roles in a variety of biological processes including cholesterol transport and signal ...
Yao Tian +20 more
doaj +2 more sources
Mapping of 20 L capacity ultrasonic reactor using cavitation activity meter and dye degradation [PDF]
Ultrasonics Sonochemistry, 2023 Mapping of a novel 20 L capacity ultrasonic (US) reactor having a total of 44 transducers was done by measuring the local cavitation intensity using a cavitation activity meter at different horizontal planes and subsequent validation based on dye ...
Shubham Joshi +2 more
doaj +2 more sources
Unraveling the Cave: A Seventy-Year Journey into the Caveolar Network, Cellular Signaling, and Human Disease [PDF]
Cells, 2023 In the mid-1950s, a groundbreaking discovery revealed the fascinating presence of caveolae, referred to as flask-shaped invaginations of the plasma membrane, sparking renewed excitement in the field of cell biology.
Alessio D’Alessio
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Role of Caveolae and Caveolin in Vascular Physiology and Pathology [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseCaveolae, 50–100 nm cholesterol‐rich plasma membrane invaginations, serve as critical signaling hubs in vascular cells. These structures—scaffolded by caveolin proteins (CAV1, CAV2, CAV3) and regulated by Cavins—orchestrate membrane dynamics ...
Chi Zhang +4 more
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