Results 61 to 70 of about 12,609 (222)

Discovery of Lacto‐N‐Biosidases and a Novel N‐Acetyllactosaminidase Activity in the CAZy Family GH20: Functional Diversity and Structural Insights

ChemBioChem
The glycoside hydrolase family 20 (GH20) predominantly features N‐acetylhexosaminidases (EC 3.2.1.52), with only few known lacto‐N‐biosidases (EC 3.2.1.140; LNBases).
M. Vuillemin, Jan Muschiol, Yan Zhang, J. Holck, Kristian Barrett, J. Preben Morth, Anne S. Meyer, Birgitte Zeuner   +7 more
semanticscholar   +1 more source

Characterization of a feruloyl esterase from Aspergillus terreus facilitates the division of fungal enzymes from Carbohydrate Esterase family 1 of the carbohydrate‐active enzymes (CAZy) database

Microbial Biotechnology, 2018
Feruloyl esterases (FAEs) are accessory enzymes for plant biomass degradation, which catalyse hydrolysis of carboxylic ester linkages between hydroxycinnamic acids and plant cell‐wall carbohydrates.
M. Mäkelä, A. Dilokpimol, Salla Koskela, Jaana Kuuskeri, R. D. de Vries, K. Hildén   +5 more
semanticscholar   +1 more source

Metagenomic Association Uncovers Host Genotype‐Structured Rhizobacterial Networks and Novel Taxa That Enhance Soybean Salt Tolerance

Advanced Science, EarlyView.
An STI‐guided metagenomic association framework links soybean salt‐tolerance phenotypes with rhizosphere microbiome composition and network organization in natural saline soils. The approach identifies candidate beneficial taxa, including Thalassospira xiamenensis, and provides an efficient strategy for mining stress‐protective microbes from native ...
Yu Luo, Feng‐Li Kang, Qi‐Min Li, Wei‐Cai Yang   +3 more
wiley   +1 more source

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

Advanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi, Ruirui Xu, Daoan Wang, Guobin Yin, Xinjing Wang, Haiqin Chen, Guocheng Du, Jian Chen, Zhen Kang   +8 more
wiley   +1 more source

Distribution of CAZy domains in predicted proteins of six Dothideomycetes.

, 2014
The classes of CAZy domains are Auxiliary Activities (AA) Carbohydrate Binding Modules (CBM), Carbohydrate Esterases (CE), Glycosyl Hydrolases (GH), Glycosyl Tranferases (GT) Polysaccharide lyases (PL). Some genes contain multiple CAZy domains.
Jonathan Grandaubert (531719), Bethany L. Clark (605308), Thierry Rouxel (121874), Andrew Cassin (468300), Rohan G. T. Lowe (330781), Angela P. Van de Wouw (238188), Barbara J. Howlett (209058)   +6 more
core   +1 more source

Unraveling the diversity within CAZy families related to hemicellulose degradation [PDF]

, 2022
Agro-food industrial side streams known as lignocellulosic wastes have received much attention in the last years. These side streams are rich in cellulose, hemicellulose and lignin and can be converted into an array of value-added bioproducts with huge ...
Li, Xinxin
core  

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

rodrigovrgs/cazy-parser: cazy-parser [page_index_fix]

, 2017
<p>Fixed an issue when obtaining page indexes</p ...
Rodrigo, Arfon Smith
core   +1 more source

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

Advanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song, Xinmin Li, Hongbo Yu, Le Xiong, Guixia Liu, Weihua Li, Yun Tang   +6 more
wiley   +1 more source

N-Acetylglucosaminidases from CAZy Family GH3 Are Really Glycoside Phosphorylases, Thereby Explaining Their Use of Histidine as an Acid/Base Catalyst in Place of Glutamic Acid*

Journal of Biological Chemistry, 2014
Background: GH3 β-N-acetylglucosaminidases atypically employ a His-Asp dyad as a catalytic acid base. Results: Enzymes from this GH3 subfamily are phosphorylases rather than hydrolases. Conclusion: Replacement of the Glu acid/base by His avoids Coulombic
S. Macdonald, M. Blaukopf, S. Withers
semanticscholar   +1 more source