Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action
Sialidases are glycoside hydrolases that cleave sialosides. Here the authors define the 3-D structure, alone and in complex with products and inhibitors, of the CAZy family GH156 sialidase, EnvSia156, showing it displays a catalytical (β/α) 8-barrel ...
Pedro Bule +9 more
doaj +1 more source
Mining the biomass deconstructing capabilities of rice yellow stem borer symbionts
Background Efficient deconstruction of lignocellulosic biomass into simple sugars in an economically viable manner is a prerequisite for its global acceptance as a feedstock in bioethanol production.
Rahul Singh +9 more
doaj +1 more source
Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang +7 more
wiley +1 more source
CAZy-HABench30K: A Homology-Aware Benchmark Dataset for CAZy Enzyme Family Classification
This dataset contains the CAZy-HABench30K benchmark used for homology-aware CAZy enzyme family classification. The dataset includes 30,000 protein sequences collected from UniProt and annotated with CAZy family and class labels.
Yurttakal, Ahmet Haşim
core +1 more source
Structural analysis ofClostridium acetobutylicumATCC 824 glycoside hydrolase from CAZy family GH105 [PDF]
Clostridium acetobutylicumATCC 824 gene CA_C0359 encodes a putative unsaturated rhamnogalacturonyl hydrolase (URH) with distant amino-acid sequence homology to YteR ofBacillus subtilisstrain 168. YteR, like other URHs, has core structural homology to unsaturated glucuronyl hydrolases, but hydrolyzes the unsaturated disaccharide derivative of ...
Germane, Katherine L. +4 more
openaire +2 more sources
Infection mechanisms of Rhizoctonia cerealis in wheat
We discover that R. cerealis (Rc) is a primary pathogen causing sharp eyespot of wheat after 335 distinct isolates were isolated from 1683 SE‐diseased wheat plants across China over 7 years using a single hyphal tip isolation method. We then generated high‐quality reference genomes via de novo sequencing of five representative Rc isolates and ...
Yan Ren +13 more
wiley +1 more source
Gut virome orchestrates nitrogen partitioning between the host and microbiome
Under normal protein intake, lytic phages promote bacterial turnover, releasing microbial nitrogen that can be assimilated by the host and thereby revealing phage‐mediated lysis as a potential pathway for host nutrient acquisition. Under protein restriction, however, phages shift toward a lysogenic strategy, reducing bacterial death and microbial ...
Shujie Xu +7 more
wiley +1 more source
Slope aspect affects the soil microbial communities in karst tiankeng negative landforms
Background Karst tiankeng is a large-scale negative surface terrain, and slope aspects affect the soil conditions, vegetation and microbial flora in the tiankeng.
Cong Jiang +3 more
doaj +1 more source
Helicobacter hepaticus Hh0072 gene encodes a novel α1-3-fucosyltransferase belonging to CAZy GT11 family [PDF]
Lewis x (Le(x)) and sialyl Lewis x (SLe(x))-containing glycans play important roles in numerous physiological and pathological processes. The key enzyme for the final step formation of these Lewis antigens is alpha1-3-fucosyltransferase. Here we report molecular cloning and functional expression of a novel Helicobacter hepaticus alpha1-3 ...
Lei, Zhang +10 more
openaire +2 more sources
ABSTRACT Afforestation is widely advocated for boosting carbon (C) sequestration. However, the stability of soil C pools in economically and culturally significant mulberry plantations remains poorly understood. The soil organic C (SOC) contents in different aggregates and the oxidizable OC fractions were measured.
Zi Yang +8 more
wiley +1 more source

