Results 101 to 110 of about 27,782 (204)

Inhibition of peripheral CB1 receptors modulates food intake and metabolic efficiency in obesity independently of the gut–brain vagal axis

British Journal of Pharmacology, Volume 183, Issue 16, Page 4953-4968, August 2026.
Background and Purpose Obesity involves profound disruptions in neuronal circuits, neuroendocrine communication and the endocannabinoid system. While global blockade of cannabinoid CB1 receptors improves metabolism, its clinical use is limited by neuropsychiatric side effects.
Oriane Onimus, Camille de Almeida, Benoit Bertrand, Julien Castel, Nejmeh Mashhour, Anthony Ansoult, Serge Luquet, Giuseppe Gangarossa   +7 more
wiley   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4512-4531, August 2026.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

The tree‐parasitic fungus Cryphonectria carpinicola discovered on European chestnut and European hornbeam in Azerbaijan

EPPO Bulletin, Volume 56, Issue 2, Page 370-375, August 2026.
Abstract The ascomycetous fungus Cryphonectria carpinicola is typically found in its asexual form on the European hornbeam, and its sexual state has only recently been discovered in deadwood of different Carpinus species in Japan. Recently, this fungus has been added to the EPPO Alert List due to its increasing incidence in the EPPO region and a ...
Carolina Cornejo, Dilzara Aghayeva, Ludwig Beenken   +2 more
wiley   +1 more source

Nondestructive Testing of Welded Composite Metal Foams

Advanced Engineering Materials, Volume 28, Issue 14, 22 July 2026.
X‐ray computed tomography (CT) is used to evaluate welded steel–steel composite metal foam (CMF) joints of two density classes. It reports variation in postweld spatial void distribution and correlates it to weld‐induced changes, mechanical performance, and failure within welded CMF panels.
Chinmaya Prerana Inguva, Aman Kaushik, Afsaneh Rabiei   +2 more
wiley   +1 more source

Special Issue on the Promise of Psychedelic Pharmacology in Neuropsychiatric Drug Development

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
Andreas Halman, Ross Corriden
wiley   +1 more source

AB-MDMSBA-Not a Synthetic Cannabinoid Receptor Agonist. [PDF]

Pharmacol Res Perspect
Patel M, Ganeshan D, Horgan I, Partington H, Glass M.   +4 more
europepmc   +1 more source

Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model. [PDF]

FASEB J
Murataeva N, Youkilis J, Rao Y, Straiker A.   +3 more
europepmc   +1 more source

Genomic and structural analysis of the endocannabinoid system in Moroccans: A novel CNR1 variant (V392A) impairs CB1 receptor stability. [PDF]

PLoS One
Abbou H, Festali R, Chemao-Elfihri MW, Hakmi M, Kartti S, Boutayeb S, Belyamani L, Eljaoudi R.   +7 more
europepmc   +1 more source

Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models. [PDF]

Aging Med (Milton)
von Borcke N, Purwien AV, Steiert A, Hasecke H, Bouter Y.   +4 more
europepmc   +1 more source

Receptor-Selective Modulation of Cannabinoid Signaling by Cardamonin: Integrating Molecular Dynamics, Free Energy Calculations, and Behavioral Validation. [PDF]

ACS Omega
Khalid MH, Azmi L, Mubarak MQE, Iqma Marsujak NM, Syahir A, Perimal EK, Sulaiman MR, Mohamad Jamali MA.   +7 more
europepmc   +1 more source